Prenatal diagnosis of autosomal dominant pseudohypoaldosteronism due to NR3C2 gene mutation. Immediate post-natal oral saline therapy prevents the clinical manifestations resulting from impaired salt balance.

Prenatal diagnosis of autosomal dominant pseudohypoaldosteronism due to NR3C2 gene mutation. Immediate post-natal oral saline therapy prevents the clinical manifestations resulting from impaired salt balance. Aaron Hanukoglu1,4, Shirli Abiri1, Dana Herzberg2, Yael Ganor Paz3,4.

The Emotional Vaccine: Maternal Caregiving in Infancy Shaped Future Preschoolers' Internalizing Symptoms During the COVID-19 Pandemic.

The present study assessed both concurrent and early influences of the maternal caregiving environment to examine unique contributions of each to variation in children's emotional responses to COVID-19 pandemic. Preschoolers (3-5 years; M = 4.12, SD = 0.

Predicting autism from young Infants' empathic responding: A prospective study.

Difficulties in empathy are frequent among children with autism spectrum disorder (ASD), and often considered a core feature of autism. Reduced empathy during the second year of life has been shown to predict subsequent ASD diagnosis. However, links between empathy in the first year and ASD have not yet been investigated.

Infant sensitivity to social contingency moderates the predictive link between early maternal reciprocity and infants' emerging social behavior.

The scientific study of love underscores the importance of dyadic reciprocity in laying the foundation for infants' social development. While research establishes links between early reciprocity and children's social capacities, some infants appear to benefit from reciprocity more than others. A central feature of reciprocity is its contingent structure, that is, the extent to which maternal behaviors are temporally associated with and contingent upon infants' dynamically changing cues.

Predictors of maternal and neonatal outcomes in labors complicated by shoulder dystocia: a comparative analysis.

Introduction: Studies investigating the risk factors associated with unfavorable maternal/neonatal outcomes in cases of shoulder dystocia are scarce. This study aims to uncover the predictive factors that give rise to unfavorable outcomes within the context of shoulder dystocia.

Materials And Methods: Medical records of pregnancies complicated by shoulder dystocia was obtained between 2008-2022 from a single tertiary center.

Placental Histopathological Lesions and Adverse Neonatal Outcomes in Patients with Inflammatory Bowel Diseases- A retrospective Cohort Study.

Inflammatory bowel diseases (IBD) are significantly associated with adverse pregnancy and neonatal outcomes, though the pathomechanism is yet unknown. To investigate the relationship between IBD and adverse pregnancy outcomes by comparing neonatal outcomes and placental histopathology in two matched groups of patients with and without IBD. In this retrospective study, data of all patients who gave birth between 2008-2021 and were diagnosed with IBD were reviewed and compared to a control group matching two control cases for every IBD case.

Does the combination of four OGTT values enhance the prediction of adverse pregnancy outcomes? Insights from a retrospective cohort study.

Aim: To explore the correlation between a singular value of additive OGTT scores and adverse maternal and neonatal outcomes. We postulated that a higher additive OGTT score would predict poorer maternal and neonatal outcomes.

Methods: In this retrospective cohort study, data were collected from all women with a documented complete OGTT result and subsequent diagnosis of GDM.

Evaluating the sensitivity to threat and affiliative reward (STAR) model in relation to the development of conduct problems and callous-unemotional traits across early adolescence.

Background: The Sensitivity to Threat and Affiliative Reward (STAR) model proposes low threat sensitivity and low affiliation as risk factors for callous-unemotional (CU) traits. Preliminary evidence for the STAR model comes from work in early childhood. However, studies are needed that explore the STAR dimensions in late childhood and adolescence when severe conduct problems (CP) emerge.

Observations of Positive Parenting from Online Parent-Child Interactions at Age 1.

Objective: Brief, reliable, and cost-effective methods to assess parenting are critical for advancing parenting research.

Design: We adapted the Three Bags task and Parent Child Interaction Rating System (PCIRS) for rating online visits with 219 parent-child dyads (White, = 104 [47.5%], Black, = 115 [52.

Promoting Empathy and Affiliation in Relationships (PEAR) study: protocol for a longitudinal study investigating the development of early childhood callous-unemotional traits.

Introduction: Children with callous-unemotional (CU) traits are at high lifetime risk of antisocial behaviour. Low affiliation (ie, social bonding difficulties) and fearlessness (ie, low threat sensitivity) are proposed risk factors for CU traits. Parenting practices (eg, harshness and low warmth) also predict risk for CU traits.

Prosocial behavior in toddlerhood and early childhood: Consistency across subtypes and over time.

Introduction: Young children show their capacity for compassion and their desire to enhance the welfare of others in multiple ways. The present study sought to address gaps in knowledge regarding prosociality in the early years. Specifically, the study examined whether different subtypes of prosociality are interrelated, whether they are consistent over time, as well as the meaning of young children's spontaneous versus cued prosocial behavior.

An informative video before planned cesarean delivery and maternal anxiety-a multicenter randomized controlled trial.

Background: Cesarean delivery is one of the most common procedures performed in obstetrics, and although cesarean delivery is a blissful occasion, it is commonly associated with fear and anxiety for the new mother.

Objective: We aimed to study the impact of watching a detailed, informative video on maternal anxiety levels, childbirth experience, and patient satisfaction in patients undergoing a primary cesarean delivery.

Study Design: We performed a multicenter randomized control trial.

Developmental trajectories of empathic concern in infancy and their links to social competence in early childhood.

Background: Empathic concern is an important component of children's social competence. Yet, little is known about the role of the development of concern for others during infancy as a predictor of social competence in early childhood.

Methods: Israeli infants (N = 165, 50% girls) were observed five times, from 3 to 36 months.

Caring babies: Concern for others in distress during infancy.

Concern for distressed others is a highly valued human capacity, but little is known about its early ontogeny. Theoretical accounts of empathy development have emphasized stages, but this has been called into question. This study sheds new light on four key issues: onset, consistency, development, and predictive power of early manifestations of concern for others.

Predicting externalizing behavior in toddlerhood from early individual differences in empathy.

Background: From middle childhood onward, there is often a negative link between empathy and externalizing behavior problems. Patterns at younger ages are still unclear, with mixed findings of no association, negative associations, and positive associations. This study examines links between empathy and externalizing problems, beginning in infancy.

Young infants are pro-victims, but it depends on the context.

The current study examined whether and when young infants are sensitive to distressed others, using two experiments with a forced-choice paradigm. Experiment 1 showed that 5- to 9-month-old infants demonstrate a clear pro-victim preference: Infants preferred a distressed character that had been physically harmed over a matched neutral character. Experiment 2 showed that infants' preference for a distressed other is not invariable, but rather depends on the context: Infants no longer preferred the distressed character when it expressed the exact same distress but for no apparent reason.

From negative reactivity to empathic responding: Infants high in negative reactivity express more empathy later in development, with the help of regulation.

Empathy has great effect on human well-being, promoting healthy relationships and social competence. Although it is increasingly acknowledged that infants show empathy toward others, individual differences in infants' empathy from the first year of life have rarely been investigated longitudinally. Here we examined how negative reactivity and regulation, two temperament traits that predict empathic responses in older children and adults, relate to infants' empathy.

Floor plate descendants in the ependyma of the adult mouse Central Nervous System.

During embryonic development of the Central Nervous System (CNS), the expression of the bHLH transcription factor Nato3 (Ferd3l) is unique and restricted to the floor plate of the neural tube. In mice lacking Nato3 the floor plate cells of the spinal cord do not fully mature, whereas in the midbrain floor plate, progenitors lose some neurogenic activity, giving rise to a reduced population of dopaminergic neurons. Since the floor plate is considered to be disintegrated at the time of birth, Nato3 expression was never tested postnatally and in adult mice.