Publications by authors named "Ya-Lin Han"
Article Synopsis
- - The study investigates the relationship between tumour mutation burden (TMB) and the prognosis of patients with stage III gastric cancer, finding that high TMB correlates with better overall survival rates.
- - Patients were categorized into high and low TMB groups using genetic sequencing and analysis, revealing that age is a key independent factor influencing prognosis, while TMB plays a significant, but secondary role.
- - The research identifies that genes frequently mutated in gastric cancer are associated with certain signaling pathways, suggesting that TMB could serve as a useful biomarker for clinical outcomes in these patients.
Lysyl oxidase and hypoxia-inducible factor 1α: biomarkers of gastric cancer.
World J Gastroenterol
April 2019
Background: Gastric cancer (GC) is one of the main causes of cancer mortality worldwide. Recent studies on tumor microenvironments have shown that tumor metabolism exerts a vital role in cancer progression.
Aim: To investigate whether lysyl oxidase (LOX) and hypoxia-inducible factor 1α (HIF1α) are prognostic and predictive biomarkers in GC.