[Influencing Mechanism of Precipitation Pollution Intensity in Qinhuai River Basin Based on Random Forest].

Analyzing the distribution characteristics of precipitation pollution intensity in the basin and identifying the main factors affecting the precipitation pollution intensity are the important basis for realizing the accurate management of diffused pollution. Based on the surface water quality data from four typical sections of the main stream of Qinhuai River Basin and rainfall data collected from 2021 to 2022, the distribution characteristics of precipitation pollution intensity in the basin were analyzed, and representative natural and social factors were selected to construct models of the precipitation pollution intensity of ammonia nitrogen （NH-N）, permanganate index, and total phosphorus （TP） based on random forest algorithm. Additionally, the main driving factors of precipitation pollution intensity were identified, and the influencing mechanism was analyzed.

Gut microbiota-involved metabolism and intestinal absorption mechanisms in decreasing bioaccessibility of triadimefon in strawberry and grape.

Gut microbiota-involved metabolism and intestinal absorption affecting bioaccessibility of triadimefon in strawberry and grape were investigated for the first time by coupling the in vitro digestion model with the Caco-2 cell model. Results showed that the gut microbiota decreased the bioaccessibility of triadimefon in strawberry by 31.00% but failed in grape, probably due to a negative modulation of the colon bacterial activity by dietary components in grapes.

Gut microbiota influence on oral bioaccessibility and intestinal transport of pesticides in Chaenomeles speciosa.

There is limited research focusing on the effects of human gut microbiota on the oral bioaccessibility and intestinal absorption of pesticide residues in food. In the present study, we use a modified setup of the Simulator of the Human Intestinal Microbial Ecosystem for the determination of pesticide residue bioaccessibility in Chaenomeles speciosa, and a Caco-2 cell model of human intestinal absorption. Results showed that gut microbiota played a dual role based their effects on contaminant release and metabolism in the bioaccessibility assay, and Lactobacillus plantarum was one of key bacterial species in the gut microbiota that influenced pesticide stability significantly.