Publications by authors named "Xin-Ru Lin"
Long-Term Temporal Profile of Motor Recovery After Intracerebral Hemorrhage.
Ann Clin Transl Neurol
August 2025
Objective: Limited data is available to describe the temporal profile of long-term recovery over 1 year after the stroke in patients with spontaneous intracerebral hemorrhage (ICH).
Methods: A registered multicentral cohort was conducted to consecutively include non-herniated supratentorial ICH patients from November 2013 to January 2023. Eligible patients received follow-ups at the time of 3 months, 6 months, 1 year, and each year after the enrollments until death or the study termination.
Amaranth Plants with Various Color Phenotypes Recruit Different Soil Microorganisms in the Rhizosphere.
Plants (Basel)
August 2024
Article Synopsis
- High-throughput sequencing technology was used to analyze soil microorganisms in the rhizosphere of red and green amaranth varieties, revealing notable differences in microbial compositions based on plant color.
- Red amaranth exhibited unique dominant soil bacterial genera, while green amaranth had its own distinct dominant bacterial genera, indicating a selective recruitment of microbes.
- Although soil fungal compositions were similar between the two varieties, the abundance of specific fungal genera varied significantly, suggesting that the presence of certain microorganisms may influence the color characteristics of amaranth.
High Plasma Fibrinogen Level Elevates the Risk of Cardiac Complications Following Spontaneous Intracerebral Hemorrhage.
World Neurosurg
December 2023
Background: Cardiac complications are related to poor prognosis after spontaneous intracerebral hemorrhage (ICH). This study aims to predict the cardiac complications arising from small intracranial hematoma at ultraearly stage.
Methods: The data of this work were derived from the Risk Stratification and Minimally Invasive Surgery in Acute ICH Patients study (ClinicalTrials.
Article Synopsis
- Hypoxic-ischemic encephalopathy is a serious condition in newborns with high rates of morbidity and limited treatment options, leading researchers to study it in neonatal rats.
- The study used a specific rat model to compare effects of hypoxic-ischemic reperfusion brain injury versus simple hypoxic-ischemic brain injury, revealing that mitochondrial proteins and signs of ferroptosis were prevalent in the reperfusion model.
- Results indicated that reperfusion worsens brain injury while also triggering protective responses related to ferroptosis, suggesting new directions for treatment and understanding of the condition in neonates.
A novel TCF-aza-BODIPY-based near-infrared fluorescent probe for highly selective detection of hypochlorous acid in living cells.
Spectrochim Acta A Mol Biomol Spectrosc
October 2022
Article Synopsis
- Hypochlorous acid/hypochlorite (HOCl/ClO) is crucial for killing bacteria and can cause tissue damage, making the development of effective fluorescent probes for detecting its levels important.
- A novel near-infrared fluorescent probe based on TCF-aza-BODIPY was designed and tested, showing good selectivity and sensitivity for detecting HOCl/ClO at 670 nm with a low background.
- This probe demonstrated a detection limit of 0.36 μM, and experiments confirmed its effectiveness in detecting both exogenous and endogenous HOCl in living cells through fluorescence enhancement.
Article Synopsis
- Sulfosalicylic acid (SUA) has low bio-degradability, making its environmental discharge a growing concern, prompting research into advanced oxidation processes for degradation.
- The study introduces a novel CoO-decorated nitrogen-doped carbon form (CONCF) as an effective catalyst for activating Oxone, outperforming traditional CoO nanoparticles by rapidly degrading SUA.
- The findings suggest that CONCF's unique properties and higher catalytic activity indicate its potential as a promising solution for addressing emerging environmental contaminants.