Dermal fillers such as calcium hydroxyapatite-carboxymethylcellulose (CaHA-CMC), polycaprolactone (PCL), and poly-l-lactic acid (PLLA) are increasingly used as 'biostimulators' to stimulate native collagen production for longer-lasting aesthetic improvement. Volume replacement should, ideally, renew local tissue architectures and functions, but the replaced volume may not align structurally or functionally with the original tissue. The ability to achieve this regenerative, biostimulatory aesthetic rejuvenation requires a thorough understanding of the principles and mechanisms of tissue regeneration and its proper application.
View Article and Find Full Text PDFBackground: Globally, there has been a notable increase in interest and demand for aesthetic treatments among men in recent years. Given the rising trend, it is important to recognize and understand the distinctions in facial anatomy and aesthetic preferences between genders and different ethnicities. When designing treatment for male patients, these differences should be taken into consideration.
View Article and Find Full Text PDFJ Cosmet Dermatol
January 2025
Background: Intradermal injection of CPM-HA20G, a low-viscoelasticity hyaluronic acid (HA) dermal filler with glycerol, has been shown to be effective for facial rejuvenation in Caucasians, but research in Asians is limited.
Aims: This study aimed to evaluate the effectiveness and safety of CPM-HA20G in enhancing facial skin quality in Korean women using a protocol developed by local aesthetic experts.
Patients/methods: In this 24-week prospective, single-arm, open-label study, 20 women received CPM-HA20G injections in the immediate subdermal layer on the anterior cheek (1 mL per side; total 2 mL) in three sessions every 4 weeks.
Plast Reconstr Surg Glob Open
May 2023
Facial skin quality profoundly influences an individual's perceived appearance and is an important aspect of facial rejuvenation. Facial pore enlargement is one of the most common concerns among Asian individuals that adversely impacts perceived skin surface evenness and affects overall skin quality. One of the major causes of enlarged pores is facial skin laxity.
View Article and Find Full Text PDFAcute graft-versus-host disease (GVHD) is a life-threatening complication of allogeneic bone marrow transplantation. It is important to recognize the dermatologic manifestations of acute GVHD, as skin is often the initial organ of involvement. We present a case of acute GVHD characterized by rare clinical and histopathologic findings as only two erythematous nodules clinically and abrupt follicular wall necrosis histopathologically.
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