Iatrogenic posterior retinal break from intravitreal anti-VEGF injection in a vitrectomized eye.

Purpose: To describe a case of a perforating fluid stream of aflibercept resulting in an iatrogenic retinal break with possible subretinal infiltration using a pre-filled syringe (PFS).

Methods: History, examination, fundus photography, and SD-OCTs.

Results: A 60-year-old female with diabetic macular edema (DME) OU was treated with intravitreal aflibercept (IVA) injections with a PFS.