CO Is Beneficial to Gut Microbiota Homeostasis during Colonoscopy: Randomized Controlled Trial.

Background: Many studies have reported minor complications and disturbance of the gut microbiota after colonoscopy. Compared with air, carbon dioxide (CO) insufflation could decrease minor complications, but its impact on gut microbiota remains unknown.

Methods: Thirty-eight healthy subjects were assessed and twenty were randomized to receive either CO or air insufflation during colonoscopy.