Publications by authors named "Wahib Zafar"

Follicular lymphoma is a common form of non-Hodgkin lymphoma. Extranodal involvement, especially in soft tissue, is rare. Here, we present a case of a 68-year-old female patient who presented with a recurrent swollen cheek, which was initially misdiagnosed as seasonal allergies.

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Primary classic Hodgkin lymphoma (HL) of the breast is a rare type of breast disease. The diagnosis is mostly confirmed by an excisional biopsy. The first line of treatment commonly used for Hodgkin lymphoma is doxorubicin, bleomycin, vinblastine, and dacarbazine (ABVD).

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Spontaneous regression of cancer is a rarely recognized entity in modern medicine. Historically, this was recognized and hypothesized that an infection causes immune activation, indirectly stimulating the body to destroy tumor cells. Similarly, immune-oncology has now become a major modality in the treatment of solid and some liquid malignancies.

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Background: Few studies have addressed the efficacy of pembrolizumab in pulmonary sarcomatoid carcinoma (PSC), a rare, previously rapidly fatal subtype of non-small-cell lung cancer.

Case Summary: We report the case of a 69-year-old man presented with respiratory distress caused by a large left upper lung lobe mass diagnosed as PSC with programmed death-ligand 1 expressed on more than 50 percent of tumor cells. The patient was started on pembrolizumab and, after 5 cycles, there was a more than 80 percent decrease in the size of the tumor mass.

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Cancer of the small bowel (SB) is rare. The most common SB malignancy is neuroendocrine, followed by adenocarcinoma. SB adenocarcinoma with overlapping neuroendocrine differentiation (NED) is very uncommon.

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Article Synopsis
  • Burkitt lymphoma is a fast-growing cancer most often seen in African children, primarily affecting the jaw and facial bones, but can also occur in immunocompromised individuals within the gastrointestinal tract.
  • This lymphoma variant is particularly unusual in the duodenum, contributing to less than 1% of all lymphomas, with limited information available on its occurrence in this area.
  • A case report highlights an older patient diagnosed with duodenal Burkitt lymphoma via biopsy, emphasizing the need for careful evaluation of immunocompromised patients who exhibit chronic abdominal issues, as early intervention can lead to better treatment outcomes.
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Conventional combination therapies have not resulted in considerable progress in the treatment of acute myeloid leukemia (AML). Elderly patients with AML and poor risk factors have grave prognosis. Midostaurin has been recently approved for the treatment of FLT-3-mutated AML.

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Dasatinib is a common anticancer drug used in the treatment of leukemia. Several side effects have been reported, the most common being myelosuppression, diarrhea, edema, and nausea. Three papers have been published reporting hepatic side effects of dasatinib treatment.

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Acute compartment syndrome is a serious condition requiring immediate medical care. A lack of urgent medical treatment can result in serious complications such as loss of function and even amputation. While the pathophysiology of acute compartment syndrome is well understood, numerous potential causes are still being discovered.

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We report the case of a 47 year-old female with Streptococcus agalactiae (Group B beta-hemolytic streptococcus) meningitis complicated by hemorrhagic stroke. The patient presented to the emergency department with altered mental status, agitation, confusion, respiratory distress and fever of one-day duration. Labs showed left shift leukocytosis.

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