Publications by authors named "Volodymyr D Markovskyi"
Objective: Aim: To study peculiarities of the state of extracellular matrix in testicular embryonal carcinoma.
Patients And Methods: Materials and Methods: Samples of testicular embryonal carcinoma tissue were collected from 3 groups of patients (group «1» - stages T1N0S0-2, group «2» - T2N1-3S0-2, group «3» - T2-3N0-3S0-2 with distant metastases) to assess the state of its extracellular matrix investigating MMP-1, MMP-3 and MMP-9 expression.
Results: Results: The levels of MMP-1, MMP-3 and MMP-9 expression were statistically significantly higher in patients with tumorous vascular/lymphatic invasion, metastases in regional lymph nodes, distant metastases and invasion into the spermatic cord (except of lightness of MMP-3 expression) in comparison with patients without these characteristics.