Foveal actual defect (FAD): A novel OCT biomarker for prognosis and surgical decision support in idiopathic full-thickness macular hole.

Background: The current classification of idiopathic full thickness macular holes (IFTMH) based on the minimum linear diameter (MLD) parameter does not provide the surgeon with accurate prognostic information regarding the surgical outcome.

Purpose: To investigate whether the preoperative Foveal Actual Defect (FAD) can predict postoperative macular hole outcomes and could be a key point in new Decision Support System for IFTMHs surgery.

Patients And Methods: Fifty-seven eyes of fifty-three patients with iFTMH, who underwent 25-gauge PPV, ILM peeling and gas tamponade (GT) were recruited for this retrospective, consecutive case, interventional study.