Publications by authors named "Vinitra Nathan"
A novel quinone biosynthetic pathway illuminates the evolution of aerobic metabolism.
Proc Natl Acad Sci U S A
February 2025
The dominant organisms in modern oxic ecosystems rely on respiratory quinones with high redox potential (HPQs) for electron transport in aerobic respiration and photosynthesis. The diversification of quinones, from low redox potential (LPQ) in anaerobes to HPQs in aerobes, is assumed to have followed Earth's surface oxygenation ~2.3 billion years ago.
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- Hopanoid lipids are unique bacterial membrane components used as biomarkers in geological records but their sources in aquatic environments are not well understood.
- Recent studies indicate that various marine bacterioplankton, particularly nitrifying bacteria, have the potential to synthesize these hopanoids.
- Analysis of hopanoid biosynthesis genes in different nitrifying bacteria shows that the production of diverse hopanoids is common, influenced by environmental factors like oxygen and nitrite availability.
The case for biotech on Mars.
Nat Biotechnol
April 2020
Innovation to improve patient care quality is a priority of the neurosurgical specialty since its beginnings. As the strain on health care resources increases, the cost of these quality improvements is becoming increasingly important. The aims of this article are to review the available tools for assessing the cost of quality improvement along with the willingness to pay and to provide a conceptual framework for the assessment of innovations in terms of quality and economic metrics and provide examples from the neurosurgical literature.
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