Integrating toda embroidery with pre-consumer textile waste: A sustainable approach to fashion production and cultural preservation.

This research aims to develop a systematic approach for reducing pre-consumer textile waste by integrating traditional Toda embroidery techniques into garment repair. This study focuses on promoting environmental sustainability while preserving indigenous cultural heritage. Drawing parallels with the Japanese concept, which transforms broken ceramics into aesthetic enhancements, this study proposes a structured method to elevate defective textiles through Indigenous craftsmanship.

Beyond the screen: The psychological significance of ecophilia in childhood.

The environmental crisis, fuelled by rapid urbanization, technology, and changing lifestyles, threatens humanity. Children's disconnection from nature negatively impacts their physical, mental, and environmental well-being, increasing their risk of psychological distress, including elevated stress levels, impaired emotional stability and cognitive function, diminished social interactions, and increased susceptibility to anxiety, depression, lower self-esteem, and reduced overall life satisfaction. Consequently, environmental risks have impact on the health and development of the children from early childhood to adolescence and then to adult life.

Characterizing Parkinson's Disease-Associated Pain in Native Patients with Malayalam Version of the King's Parkinson's Disease Pain Scale.

Background And Objectives: Pain is an important non-motor symptom in Parkinson's disease (PD) and is often under-recognized. Pain is also a symptom frequently reported by non-PD elderly subjects. The King's Parkinson's Disease Pain Scale (KPPS) is a valid tool to characterize and quantify pain in PD and has been translated into several languages.

Sign, Signifier and Signified in Schrödinger's box.

This study of the article proposes an interdisciplinary approach, integrating quantum mechanics and structuralism to elucidate the complex dynamics of signification. By paralleling the ambiguous nature of subatomic particles with the linguistic system, the study examines the arbitrary relationship between sign, signifier, and signified through quantum principles. Key concepts from quantum mechanics, such as wave-particle duality, superposition, entanglement, and observer effect, are applied to Saussure's theory of signs, revealing intriguing analogies between the two domains.

Quantifying abnormal writing kinematics in writer's cramp using a novel software platform.

Background: Writer's cramp is a task-specific focal hand dystonia, which is diagnosed clinically. Quantification of defect in WC is done using clinical scales, while digitized platforms are lacking.

Objective: To design and test a platform that can differentiate and quantify the abnormal kinematics of writing using a software interface and to validate it in adult-onset isolated writer's cramp (WC).

Unravelling the Parkinson's puzzle, from medications and surgery to stem cells and genes: a comprehensive review of current and future management strategies.

Parkinson's disease (PD) is a neurodegenerative disorder, prevalent in the elderly population. Neuropathological hallmarks of PD include loss of dopaminergic cells in the nigro-striatal pathway and deposition of alpha-synuclein protein in the neurons and synaptic terminals, which lead to a complex presentation of motor and non-motor symptoms. This review focuses on various aspects of PD, from clinical diagnosis to currently accepted treatment options, such as pharmacological management through dopamine replacement and surgical techniques such as deep brain stimulation (DBS).

Quantitative susceptibility mapping from basal ganglia and related structures: correlation with disease severity in progressive supranuclear palsy.

Objective: We examined whether mean magnetic susceptibility values from deep gray matter structures in patients with progressive supranuclear palsy (PSP) differed from those in patients with Parkinson's disease (PD) and healthy volunteers, and correlated with the PSP rating scale.

Methods: Head of caudate nucleus, putamen, globus pallidus, substantia nigra and red nucleus were the regions of interest. Mean susceptibility values from these regions in PSP patients were estimated using quantitative susceptibility mapping.

Cerebellar and basal ganglia structural connections in humans: Effect of aging and relation with memory and learning.

Introduction: The cerebellum and basal ganglia were initially considered anatomically distinct regions, each connected thalamic relays which project to the same cerebral cortical targets, such as the motor cortex. In the last two decades, transneuronal viral transport studies in non-human primates showed bidirectional connections between the cerebellum and basal ganglia at the subcortical level, without involving the cerebral cortical motor areas. These findings have significant implications for our understanding of neurodevelopmental and neurodegenerative diseases.