Publications by authors named "Vanessa Brzoskowski Dos Santos"
Purpose: This study investigates whether speech changes over time in patients with different motor subtypes of Parkinson's disease (PD).
Methods: This longitudinal study included 60 individuals with PD, classified into tremor-dominant (n = 42) and non-tremor-dominant (n = 18) subtypes according to the Movement Disorder Society Unified Parkinson's Disease Rating Scale. Participants were assessed at three points: baseline, 12 months, and 24 months.
Background: Parkinson's disease (PD) is a heterogeneous disorder, suggesting the presence of distinct subtypes. Speech data, though easy to collect, remains underutilized in subtyping PD.
Methods: Cross-sectional study with PD patients recruited from the Movement Disorders Outpatient Clinic of the Neurology Service at the University Hospital in Porto Alegre, Brazil.
Speech Characteristics Across Motor Subtypes of Parkinson's Disease.
Int J Lang Commun Disord
July 2025
Background: Speech differences may occur between motor subtypes of Parkinson's disease (PD), but the literature remains limited.
Aims: Examine speech characteristics in individuals with PD across the tremor-dominant, nontremor-dominant and mixed subtypes comparing to healthy controls.
Methods And Procedures: A total of 115 individuals with PD were included in the study, classified as tremor-dominant (n = 61), nontremor-dominant (n = 39) and mixed (n = 15) subtypes according to the Movement Disorder Society - Unified Parkinson's Disease Rating Scale.
Purpose: To compare the speech and voice patterns of myasthenia gravis (MG) patients over four years, and correlate the results with clinical aspects of the disease.
Methods: Data was collected for 4 years. The clinical assessment tools included the Quantitative Myasthenia Gravis (QMG) score, the Myasthenia Gravis Foundation of America (MGFA) clinical classification, and the Myasthenia Gravis Quality of Life 15-item Scale (MG-QoL).
Background: Dysarthria is one of the most frequent communication disorders in patients with Multiple Sclerosis (MS), with an estimated prevalence of around 50%. However, it is unclear if there is a relationship between dysarthria and the severity or duration of the disease.
Objective: Describe the speech pattern in MS, correlate with clinical data, and compare with controls.
Article Synopsis
- The study investigates how speech is affected in patients with disorders of the basal ganglia (like Parkinson's disease) compared to those with cerebellar disorders (like spinocerebellar ataxia type 3).
- It includes 20 patients with Parkinson's, 20 with SCA3, and 40 healthy controls, analyzing their speech through specific tasks.
- Results show that SCA3 patients produced fewer syllables in monologs compared to controls, while PD patients had even lower syllable counts and phonation times, indicating that monolog tasks can effectively differentiate between these conditions and correlate with disease severity.
Association between acute disease severity and one-year quality of life among post-hospitalisation COVID-19 patients: Coalition VII prospective cohort study.
Intensive Care Med
February 2023
Purpose: To assess the association between acute disease severity and 1-year quality of life in patients discharged after hospitalisation due to coronavirus disease 2019 (COVID-19).
Methods: We conducted a prospective cohort study nested in 5 randomised clinical trials between March 2020 and March 2022 at 84 sites in Brazil. Adult post-hospitalisation COVID-19 patients were followed for 1 year.
Dysarthria in hereditary spastic paraplegia type 4.
Clinics (Sao Paulo)
December 2022
Objective: To describe the speech pattern of patients with hereditary Spastic Paraplegia type 4 (SPG4) and correlated it with their clinical data.
Methods: Cross-sectional study was carried out in two university hospitals in Brazil. Two groups participated in the study: the case group (n = 28) with a confirmed genetic diagnosis for SPG4 and a control group (n = 17) matched for sex and age.
Unlabelled: Although it is predominantly a muscular disease, impairments in the central nervous system in patients with facioscapulohumeral muscular dystrophy (FSHD) have been described in the literature.
Objective: To describe the cognitive profile of patients with FSHD and to correlate the impairments found with clinical variables and quality of life.
Methods: Cross-sectional and case-control study that evaluated FSHD patients using a series of cognitive assessments (Mini-Mental State Examination - MMSE, Montreal Cognitive Assessment - MoCA, verbal fluency with phonological restriction - FAS, categorical verbal fluency - FAS-cat, trail-making test - TMT, and Rey's Verbal Auditory Learning Test); a neurological severity scale (Gardner-Medwin-Walton - GMWS); and a quality of life measurement tool (Medical Outcomes Study 36-Item Short-Form Health Survey).
Background: Although facial muscle weakness is common in patients with Facioscapulohumeral Muscular Dystrophy (FSHD), the literature is scarce on the speech and swallowing aspects.
Objective: To investigate speech and swallowing patterns in FSHD and assess the correlation with clinical data.
Methods: A cross-sectional study was conducted.