Borderline Personal Disord Emot Dysregul
August 2025
Background: Borderline Personality Disorder (BPD) is a complex mental health condition characterized by pervasive instability in mood, interpersonal relationships, self-concepts, and behavior. A reliable assessment of BPD symptom severity is essential for effective treatment planning and evaluation. This study introduces and evaluates the Borderline Symptom List Interview (BSL-I), a semi-structured interview designed to assess the severity of BPD symptoms comprehensively.
View Article and Find Full Text PDFBackground: Post-COVID condition is most commonly associated with physical symptoms such as dyspnea on exertion, difficulty in concentration, fatigue, and frailty but meta-analyses also document high rates of mental health problems such as anxiety disorders, depression, and post-traumatic stress disorder (PTSD).
Methods And Findings: In the current study, 140 persons (66% female) receiving inpatient pulmonary rehabilitation treatment for post-COVID condition for an average of 27 days (SD = 11) completed self-report measures on mental and physical health at admission and discharge. At admission, 54%, 36%, 36%, and 14% screened positively for somatoform syndrome, generalized anxiety, depression, and PTSD, respectively.
Background: Inpatient treatment successfully increases body weight and decreases eating disorder and associated symptoms in patients with anorexia nervosa (AN). However, relapse rates are high, particularly within the first year after discharge.
Methods: We examined treatment outcome one year after discharge in adults with AN (N = 80, 2 males; BMI at admission: M = 13.
J Behav Ther Exp Psychiatry
December 2025
Background: Therapeutic climbing (TC) is increasingly used as a therapy form in psychosomatic settings. Recent studies have shown its effectiveness in terms of symptom severity and other psychological factors compared to other sports and even to group cognitive behavioural therapy. To gain a deeper understanding of TC, the present study aimed to qualitatively explore the patients' perspectives.
View Article and Find Full Text PDFNeurosci Biobehav Rev
August 2025
Obsessive-compulsive disorder (OCD) is a severe and common mental illness associated with high rates of treatment resistance. Quality of life is significantly impaired by OCD, and there is a high risk of chronification without treatment. The rationale of this narrative review is to present the state of the art about OCD regarding its A) relevance, course, and impact on wellbeing, B) risk factors, C) etiopathophysiology, D) clinical manifestation and classification criteria, E) comorbidity and differential diagnostics, F) diagnostic investigations, G) secondary obsessive-compulsive syndromes, and H) treatment approaches.
View Article and Find Full Text PDFBackground: The accurate diagnosis of mental disorders, such as depression, requires comprehensive, valid, and reliable tools to ensure evidence-based treatments and effective outcome monitoring. Existing diagnostic practices often lack standardization, leading to missed comorbidities and variable diagnostic accuracy. The Klenico system is an innovative, web-based diagnostic tool that integrates patient self-reports with clinical validations by mental health professionals.
View Article and Find Full Text PDFObsessive-compulsive disorders (OCD) are common and have high treatment resistance rates. The rationale of this CME article is to provide an update on OCD in adulthood. First, recent study results on the etiopathogenesis of OCD and its correlates are summarized and the clinical manifestations and current classification criteria are presented.
View Article and Find Full Text PDFJ Psychiatr Res
September 2025
Emetophobia refers to a fear that oneself or others might vomit and is classified as a specific phobia in current diagnostic manuals. However, it is a relatively unknown and understudied mental disorder. Although it has been speculated that emetophobia might differ from other specific phobias (e.
View Article and Find Full Text PDFObjective: Although childhood maltreatment, especially emotional abuse, is strongly linked to the psychopathology of anorexia nervosa (AN), the impact of such a traumatic experience on treatment outcome is not clear. This study aimed to explore how emotional abuse affects change in psychopathology during treatment.
Method: Adolescents with AN (n = 331) completed the Childhood Trauma Questionnaire at admission to inpatient treatment and the Eating Disorder Inventory-2, Patient Health Questionnaire-9, Patient Health Questionnaire-15, and Generalized Anxiety Disorder-7 both at admission and at discharge.
Driven exercise is a transdiagnostic maladaptive behavior, especially common in eating disorders (ED); however, its maintenance mechanisms remain poorly understood. To address this gap, we examined the applicability of previously empirically-derived and validated reinforcement function models in explaining driven exercise maintenance in studies varying across developmental stages and clinical presentations (Study 1: =279 adolescents/adults oversampled for EDs; Study 2: =118 adolescent/adult inpatients with severe EDs; Study 3: =52 adults oversampled for athletes and/or EDs). Results supported the utility of a four-function model (automatic positive/negative reinforcement [APR/ANR; increase/decrease negative affect], social positive/negative reinforcement [SPR/SNR; engage in/avoid interpersonal situations]) in explaining driven exercise.
View Article and Find Full Text PDFAnorexia nervosa (AN) is a severe psychiatric disorder with the highest mortality rate among eating disorders. It predominantly affects adolescents and young adults, with a significant increase in prevalence among adolescents observed since the coronavirus disease 2019 (COVID-19) pandemic. It is frequently associated with other psychiatric disorders, such as depression, anxiety and obsessive-compulsive disorders as well as numerous physical complications.
View Article and Find Full Text PDFJ Eat Disord
April 2025
Background: Eating disorders (EDs) are severe psychiatric conditions, with prevalence rates ranging from 5.5 to 17.9% in women and 0.
View Article and Find Full Text PDFAnorexia nervosa (AN) is a severe psychiatric disorder with the highest mortality rate among eating disorders. It predominantly affects adolescents and young adults, with a significant increase in prevalence among adolescents observed since the coronavirus disease 2019 (COVID-19) pandemic. It is frequently associated with other psychiatric disorders, such as depression, anxiety and obsessive-compulsive disorders as well as numerous physical complications.
View Article and Find Full Text PDFObjective: Persons with bulimia nervosa (BN) often gain weight during treatment, which potentially poses a threat to treatment adherence. Although weight suppression has been found to be a predictor of weight gain in persons with BN, research about the trajectory of weight changes during treatment and other predictors thereof is scarce.
Method: The current study examined weight suppression as well as self-reported binge eating severity and purging frequency at admission as predictors of weight change in 746 persons with BN (95% female) who received inpatient treatment at the Schoen Clinic Roseneck (Prien am Chiemsee, Germany) between 2015 and 2020.
Background: Anorexia nervosa, bulimia nervosa and binge-eating disorder are severe mental illnesses and are often associated with mental comorbidities, such as depression, anxiety and obsessive-compulsive disorders. Psychotherapy is considered the primary method of treatment; however, in the clinical practice it is not uncommon to also use psychopharmacotherapy.
Material And Methods: The article considers international and national guidelines as well as the updated World Federation of Societies of Biological Psychiatry (WFSBP) guidelines to summarize the current evidence on psychopharmacotherapy of eating disorders.
Background: Bulimia nervosa (BN) is a serious mental illness with impulsivity as a cardinal symptom. Impulsivity contributes to various other, often comorbid, mental disorders, such as attention deficit/hyperactivity disorder (ADHD) and borderline personality disorder (BPD). The aim of this study was to explore comorbidities of BN with ADHD and BPD as well as the contribution of impulsivity as an underlying trait linking these disorders.
View Article and Find Full Text PDFIntroduction: Although depressive disorders are frequently associated with relapses, the sustained efficacy of therapies after their termination has been insufficiently investigated.
Objective: The aim of this study was to evaluate the current evidence of enduring effects of psychotherapy, antidepressants and their combination after the end of treatment.
Methods: PubMed and PsychINFO were systematically screened according to PRISMA guidelines (except for preregistration).
Introduction: The impact of antipsychotic use on weight gain and eating disorder-related psychopathology in adult inpatients with anorexia nervosa (AN) is unclear.
Methods: Consecutively hospitalized adults with AN were retrospectively analyzed. Co-primary outcomes were body mass index (BMI) and weekly weight change.
Objective: It is often stated that a higher body mass index (BMI) at the beginning of treatment predicts a better weight outcome at the end of treatment in persons with anorexia nervosa (AN). However, this interpretation is based on the between-persons relationship of BMI at the two measurements, which primarily reflects the fact that the rank-ordering of persons according to their BMI is quite stable over time. In contrast, a lower BMI at baseline is related to a larger BMI change, which primarily reflects the fact that the variance of BMI at the end of treatment is larger than that at baseline.
View Article and Find Full Text PDFObjective: In the Diagnostic and Statistical Manual of Mental Disorders-5, severity of bulimia nervosa (BN) is defined by the frequency of purging behaviour. Previous research suggests the number of purging methods as an alternative rating. The current analysis investigated characteristics (sociodemographic and treatment-related variables, body mass index [BMI], eating disorder-specific and general psychopathology) of persons with BN as a function of purging frequency and number of purging methods in order to examine which approach might be better suited for indicating severity of BN.
View Article and Find Full Text PDFWe previously found that rumination maintains obsessive-compulsive (OC) symptoms. Our goal was to explore the moderating roles of three characteristics in the immediate and intermediate effects of rumination on OC symptoms: trait rumination, severity of comorbid depressive symptoms, and the tendency to misinterpret the occurrence of unwanted intrusive thoughts as meaningful. We reanalyzed our previous study's data and explored in a sample of 145 individuals diagnosed with obsessive-compulsive disorder (OCD) whether any of the three characteristics moderated the observed immediate and intermediate effects of rumination on OC symptoms.
View Article and Find Full Text PDFThe Brief Resilience Scale (BRS) was developed to assess individual differences in the ability to recover from stress despite adversity and has been translated into several languages. This study aimed to examine the psychometric properties (i.e.
View Article and Find Full Text PDFInt J Eat Disord
December 2024
Objective: Assessment of the longer-term outcome of anorexia nervosa (AN) in female adolescent inpatients (N = 132).
Method: A follow-up (mean 8.2 years) after treatment was conducted.