Publications by authors named "Tugba Kevser Uzuncakmak"

Objective: Acne vulgaris is a chronic and common disease among adolescents. The effects of acne vulgaris on the caregiver's quality of life and its relationship to patient's quality of life have been seldom studied. This study aims to investigate impact of adolescent acne vulgaris on the patients' and their caregivers' quality of life and to evaluate the relationship between these two variables.

View Article and Find Full Text PDF

Alopecia areata (AA) is an autoimmune disease that develops due to inflammation and causes sudden hair loss. Ithas been observed that family circumstances may contribute to the development of AA. This study aims to assessthe relationship between the development of alopecia areata in children, family functions, and depression andanxiety levels in their parents.

View Article and Find Full Text PDF

Background: There are a limited number of studies evaluating the effects of alopecia areata (AA) on the health-related quality of life (HRQoL) of pediatric patients and their families. This study aimed to assess the HRQoL of pediatric patients with AA and their parents.

Materials And Methods: This single-center cross-sectional cohort study included 72 pediatric patients diagnosed with AA.

View Article and Find Full Text PDF
Article Synopsis
  • The study aims to analyze demographic and clinicopathological characteristics of patients with Spitz nevus, focusing on differences based on age and lesion location.
  • Researchers reviewed the cases of 32 patients from 2010 to 2020, finding that more females were affected, with most lesions occurring on the upper extremities, particularly in children.
  • Results showed distinct histological subtypes based on age: in children, the pigmented and compound variants were most common, while in adults, the desmoplastic variant prevailed, highlighting a need for further research with larger sample sizes.
View Article and Find Full Text PDF

Granulomatous skin disorders comprise a large group of diseases that are typically characterized by granuloma formation both in the skin and in many other tissues. Cutaneous lesions are usually seen as erythematous papules and plaques that may occasionally be arranged in an annular, ringlike configuration. The etiopathogenesis is unclear in most cases, and granuloma formation may be associated with various systemic, infectious, and metabolic disorders, foreign bodies, environmental antigens, or malignancies.

View Article and Find Full Text PDF

Introduction: Systemic isotretinoin is the most effective treatment modality in acne vulgaris; however, both patients and physicians hesitate to use it due its side effects.

Objectives: The aim of this study is to determine the prevalence of fatigue, myalgia and low back pain during systemic isotretinoin treatment; and to determine their relationship with age, gender, treatment duration, daily isotretinoin dose and isotretinoin-naiveness of the patient.

Methods: This is a cross sectional study including the acne vulgaris patients, aged between 13 to 40 years, who have at least received one month of oral isotretinoin treatment.

View Article and Find Full Text PDF

Background: Acne vulgaris (AV) is among the common skin diseases for which patients refer to complementary and alternative medicine (CAM).

Aims And Objectives: To investigate the approaches to CAM methods and factors believed to increase the disease in 1,571 AV patients.

Materials And Methods: The sociodemographic characteristics of the patients and disease severity according to the Food and Drug Administration criteria were recorded.

View Article and Find Full Text PDF

Objectives: Striae distensae (SD) are characterized by erythematous or atrophic bands, which are common during adolescence and can adversely impact the psychosocial status of the affected patients. Our aim in this study is to evaluate the quality of life of children and adolescents diagnosed with SD.

Methods: This prospective observational study included 50 adolescents with SD.

View Article and Find Full Text PDF

The association of glutathione S-transferase (GST) enzymes with vitiligo is inconclusive. To evaluate tissue expressions of GST isoenzymes in vitiligo patients and to compare these expressions with healthy controls, we used 26 active depigmented patches on the trunk of vitiligo patients and 20 healthy sex and age matched controls. Punch biopsies were taken from the lesioned or normal skin.

View Article and Find Full Text PDF

Background: Skincare products and cosmetic procedures are used as an adjunct or complementary to conventional drug therapy for acne vulgaris (AV).

Objective: To evaluate the use of skincare products and the frequency of cosmetic procedures in AV treatment.

Methods: A total of 1,755 patients with AV completed the survey prepared by the researchers and the Cardiff Acne Disability Index (CADI) questionnaire.

View Article and Find Full Text PDF

Periungual and subungual fibromas, also known as Koenen tumors, are diagnostic findings of tuberous sclerosis. The clinical appearance and histological features that characterize ungual fibromas are well defined. However, dermoscopic findings of these benign tumors have not been reported previously.

View Article and Find Full Text PDF

Background/aim: Alopecia areata (AA) is a common autoimmune hair disorder which is characterized by noncicatricial hair loss. AA commonly presents with localized patches on the scalp and face but may affect any hair-bearing region of the body leading to even more generalized involvement. AA may affect any age group, gender, and race.

View Article and Find Full Text PDF

Tofacitinib is a Janus Kinase 3 inhibitor that is used in the treatment of alopecia areata. We recommended our alopecia areata patients to discontinue their tofacitinib treatment during the COVID-19 pandemic for an average of 80 days. We aimed to evaluate the drug use and the SARS-CoV-2 infection status of alopecia areata patients; and the relationships of recurrence to age, gender, treatment duration, and tofacitinib discontinuation.

View Article and Find Full Text PDF

There is widespread concern about treatment of psoriasis in COVID-19 pandemic. We aimed to evaluate the epidemiological data, clinical characteristics, treatment features of the psoriasis patients during the pandemic period. We conducted a study in dermatology clinics of seven different tertiary centers.

View Article and Find Full Text PDF

The diagnosis of psoriasis is mainly made by clinical examination but on some occasions according to the localization or duration of the lesions when spongiosis is more prominent, it can be challenging and may be considered as overlapping eczema. To evaluate the patients for "eczema in psoriatico" and to present the differences between psoriasis. Biopsy outcomes of thirty-one patients who were histologically diagnosed with psoriasis and psoriasiform dermatitis because of the erythematous and scaly plaque lesions located on hands and feet, between 2013 and 2015, were evaluated retrospectively.

View Article and Find Full Text PDF

Rituximab is a monoclonal antibody that targets CD20, a B-lymphocyte antigen; that leads to a decline in the B-cell counts for at least a year. The patients who have received rituximab treatment in the previous 5 years with the diagnosis of pemphigus group of diseases at Cerrahpaşa Medical Faculty were questioned for COVID-19 infection. A total of 48 patients were included in this study; only one male patient had COVID-19 infection which had a mild course.

View Article and Find Full Text PDF