Publications by authors named "Truong D Nguyen"

Objectives: Due to its complexity, the management of cancer-related fatigue (CRF) is best based on an inter-disciplinary care approach. Thus, we examined the preferred and the actual distribution of responsibilities from the perspectives of healthcare professionals and patients.

Materials And Methods: An online survey was conducted among physicians (N =148), nurses (N =184), and psycho-oncologists (N =144) in Germany.

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Virus genomes harbor compacted repertoires of genes and regulatory elements. Through long-read sequencing, we provide a comprehensive Epstein Barr virus (EBV) transcriptome analysis, identifying 1453 transcript isoforms and resolving the major isoform of all but one lytic reading frame. Further, we categorize each transcript according to their dependence on viral DNA replication.

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Background: One of the most common sequelae of cancer and/or its treatment is cancer-related fatigue (CRF). For those affected, CRF is often accompanied by considerable, even long-term impairment. This makes it all the more important to examine how care is provided in Germany and to what extent guideline recommendations are implemented in clinical practice.

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Article Synopsis
  • * EBV initiates transcription at nearly 29,674 new genomic sites within the cell, aided by a unique viral pre-initiation complex that requires few additional transcription factors.
  • * The study highlights how EBV uses its own transcription factors to drive new promoters and interact with existing cell promoters, affecting host gene expression and providing insights into fundamental eukaryotic gene regulation.
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