Publications by authors named "Travis A Jarrell"
Article Synopsis
- Understanding connectivity in the nervous system is crucial for grasping its overall function, and this study focuses on the connectomes of the nematode C. elegans, a key model for neuroscience.
- The research features updated quantitative connectivity matrices that include connections from sensory inputs to outputs, highlighting differences between adult male and female nervous systems.
- It reveals that while some neurons are shared between sexes, they exhibit differences in structure and strength of connections, implicating both sexual and non-sexual pathways in behavior generation.
A rate-limiting step in determining a connectome, the set of all synaptic connections in a nervous system, is extraction of the relevant information from serial electron micrographs. Here we introduce a software application, Elegance, that speeds acquisition of the minimal dataset necessary, allowing the discovery of new connectomes. We have used Elegance to obtain new connectivity data in the nematode worm Caenorhabditis elegans.
View Article and Find Full Text PDFIn order to understand the nervous system, it is necessary to know the synaptic connections between the neurons, yet to date, only the wiring diagram of the adult hermaphrodite of the nematode Caenorhabditis elegans has been determined. Here, we present the wiring diagram of the posterior nervous system of the C. elegans adult male, reconstructed from serial electron micrograph sections.
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