A novel gene variant c.525_533del causing Barth syndrome and leading to heart transplantation: a case report.

Introduction: Barth syndrome (BTHS) is an ultra-rare genetic disease caused by a mutation in the gene, located on the X chromosome. This gene codes for the protein tafazzin, which is involved in the metabolism of the mitochondrial phospholipid - cardiolipin. Symptoms of this genetic defect include dilated cardiomyopathy (DCM), skeletal myopathy, neutropenia, growth retardation, reduced cholesterol levels, increased serum lactic acid levels, and hypoglycemia in the neonatal period.

Outcomes of severely impaired renal function patients with and without dialysis following isolated coronary artery surgery - a retrospective cohort study.

Objectives: Patients with advanced-stage chronic renal failure have poor outcomes following cardiac surgery. Our registry study aimed to compare postoperative and follow-up data between patients who underwent isolated coronary artery surgery with preoperative chronic dialysis and patients with preoperative severe renal impairment who did not require chronic dialysis.

Methods: We analyzed 157 948 consecutive adult patients in the Polish National Registry of Cardiac Surgical Procedures (KROK Registry) scheduled for isolated coronary artery surgery between January 2010 and December 2023.

Safe and effective antireflux surgery in lung transplant recipients: preliminary results.

Introduction: Obliterative bronchiolitis, the clinical manifestation of bronchiolitis obliterans syndrome (BOS), is a major complication of lung transplantation and one of the primary causes of chronic lung allograft dysfunction leading to poor survival outcomes.

Aim: The aim of this study was to evaluate the safety and outcomes of antireflux surgery in lung transplant recipients (LTRs) with BOS and associated gastroesophageal reflux disease (GERD).

Materials And Methods: This single-center study included 8 consecutive patients at a median (interquartile range [IQR]) age of 29 (25-46) years who underwent bilateral lung transplantation and subsequent antireflux surgery due to BOS.

Prognostic value of angiography-based fractional flow reserve of left anterior descending artery in orthotopic heart transplant recipients.

Background: Coronary angiography has limited value in predicting subsequent events in cases of no or mild cardiac allograft vasculopathy (CAV). We aimed to assess the prognostic value of angiography-based vessel fractional flow reserve (vFFR) in orthotopic heart transplant recipients.

Material And Methods: The study retrospectively included patients who underwent baseline coronary angiography after orthotopic heart transplant between 2014 and 2023 and had no obstructive CAV.

Impact of Deep Sternal Wound Infection on Long-Term Survival Based on Revascularisation Strategy: Results From the Polish National Registry.

Background: This multicentre study aimed to investigate the impact of deep sternal wound infection (DSWI) on long-term survival among patients undergoing coronary artery bypass grafting (CABG) using multiple arterial grafting (MAG) or single artery with saphenous vein grafts (SAG).

Methods: Data were obtained from the Polish National Registry of Cardiac Surgery Procedures database. Between January 2012 and December 2020, 81,136 patients who underwent CABG for multivessel disease were included in the study.

Unfavorable impact of female gender on outcomes following aortic valve replacement combined with coronary artery bypass grafting.

Despite widespread implementation of intravascular techniques in cardiovascular medicine, combined aortic valve replacement (AVR) and coronary artery bypass grafting (CABG) have still been standard of surgical treatment. A purpose of this multicenter retrospective cohort study was to assess an impact of female sex on early outcomes and late survival rate following simultaneous AVR + CABG. This study comprised 12,626 patients (30.

Could TachoSil application in cardiac surgery be potentially dangerous? A review of the literature.

The application of TachoSil adhesive is becoming increasingly popular in surgical procedures. A special area of surgical medicine is cardiac surgery, where the adhesive makes it possible to provide hemostasis when classic anastomotic methods are insufficient. There are numerous studies available demonstrating the perioperative efficacy of TachoSil, and its ease of use in the human population.

Short- and mid-term outcomes in patients undergoing transcatheter aortic valve implantation in Poland in 2019-2023.

Background: Transcatheter aortic valve implantation (TAVI) has become a cornerstone in the treatment of severe aortic stenosis, with expanding indications for lower-risk patients. However, real-world data, especially regarding post-discharge outcomes, from multicenter registries are scarce but needed.

Aims: To evaluate the in-hospital and mid-term outcomes of patients undergoing TAVI in all Polish centers between 2019 and 2023.

The Effect of Immunosuppressive Treatment on Torque Teno Virus Load in Lung Transplant Recipients: A Preliminary Study.

After transplantation, systematically monitoring and assessing the risk of transplanted organ rejection is crucial. Current methods involving immunosuppressant monitoring, the assessment of organ function, and biopsies are insufficient for predicting rejection. However, regular determination of torque teno virus (TTV) load after transplantation may prove to be a useful parameter for monitoring immunosuppression efficacy.

Outcomes of coronary artery bypass grafting in elderly patients: A comprehensive analysis of different surgical approaches (from the KROK Registry).

Background: Coronary artery revascularization is vital for managing coronary artery disease, especially in elderly patients with multiple comorbidities.

Aims: To evaluate the outcomes of coronary artery bypass surgery in patients aged ≥75 years, focusing on the survival benefits of different surgical techniques and graft types.

Material And Methods: This retrospective cohort study analyzed data from the Polish National Registry of Cardiac Surgery Procedures (2012-2022) for patients aged ≥75 years undergoing isolated coronary artery bypass surgery.

Percutaneous coronary intervention and coronary artery bypass grafting in myocardial infarction complicated by cardiogenic shock.

Background: Cardiogenic shock (CS) remains the leading cause of poor prognosis in patients with acute myocardial infarction (AMI), sustaining a high mortality rate of 40 to 50% within 30 days.

Aims: In this unique analysis of two national all-comers, real-life registries including patients with AMI complicated by CS, for whom early revascularization was planned, we aimed to compare the effect of percutaneous coronary revascularization (PCI) and coronary artery bypass grafting (CABG) on 30-day and 1-year all-cause mortality.

Methods: The study included consecutive patients with AMI complicated by CS included in the Polish Registry of Acute Coronary Syndromes (PL-ACS) and the Polish National Registry of Cardiac Surgical Procedures (KROK), treated with PCI and CABG, respectively.

Do patients with ischaemic cardiomyopathy benefit from off-pump coronary bypass surgery? (From the KROK registry).

Objectives: This study aimed to compare perioperative outcomes and long-term mortality between off-pump coronary artery bypass grafting and on-pump coronary artery bypass grafting in patients with ischaemic cardiomyopathy who had a left ventricle ejection fraction of ≤35%.

Methods: A retrospective cohort analysis was conducted using data from the Polish National Registry of Cardiac Surgery Procedures database, encompassing patients who underwent isolated coronary artery bypass grafting in Poland between 2012 and 2022. Patients were divided into two groups: on-pump and off-pump.

Pericardial mesothelioma mimicking mediastinal lymphoma and systemic rheumatic disease: a case report.

Introduction: Pericardial mesothelioma is an exceedingly rare pericardial neoplasm. It has atypical clinical symptoms and imaging characteristics that often lead to an inconclusive diagnosis. The diagnosis of a rare tumor such as pericardial mesothelioma, which can present with a variety of manifestations, requires a multidisciplinary approach.

Does the Coronary Artery Bypass Grafting Impact the Survival of Men and Women Equally Compared to General Population? Results from KROK Registry and Polish Central Statistical Office.

The aim of this study was to evaluate the impact of coronary bypass surgery (CABG) on long-term mortality, comparing survival rates to those of the general population in Poland. The study was based on the Polish National Register of Cardiothoracic Surgical Procedures (KROK). Between January 2009 and December 2019, 133,973 patients underwent CABG.

Wound Healing Complications After Sternotomy-Causes, Prevention, and Treatment-A New Look at an Old Problem.

Median sternotomy is one of the most common procedures in cardiac surgery. This corresponds to the relatively high frequency of infections where surgical incisions are performed. In the prevention of healing disorders, the medical staff intervention is important, as is the patient.

Performance of EuroSCORE II in Octogenarians Undergoing Coronary Artery Surgery (from the KROK Registry).

Octogenarians constitute the fastest-growing segment within contemporary cardiac surgery, yet precise risk assessment in this age group remains challenging. This study aimed to evaluate EuroSCORE II reliability in octogenarians undergoing isolated coronary surgery and to create an adjustment formula if necessary. All octogenarians who had isolated coronary surgery in Poland from January 2012 to December 2023, recorded in the Polish National Registry of Cardiac Surgical Procedures (KROK registry), were retrospectively assessed.

Effect of Oxidative Stress on Mitochondrial Damage and Repair in Heart Disease and Ischemic Events.

The literature analysis conducted in this review discusses the latest achievements in the identification of cardiovascular damage induced by oxidative stress with secondary platelet mitochondrial dysfunction. Damage to the platelets of mitochondria as a result of their interactions with reactive oxygen species (ROS) and reactive nitrogen species (RNS) can lead to their numerous ischemic events associated with hypoxia or hyperoxia processes in the cell. Disturbances in redox reactions in the platelet mitochondrial membrane lead to the direct oxidation of cellular macromolecules, including nucleic acids (DNA base oxidation), membrane lipids (lipid peroxidation process) and cellular proteins (formation of reducing groups in repair proteins and amino acid peroxides).

Rupture of the ascending aorta 6 months after TAVI procedure caused by TAVI prosthesis.

Background: Transcatheter aortic valve implantation (TAVI) is indicated for elderly patients who often have severe comorbidities and high operative risk. Despite many advantages, it carries the potential for both early and late complications. The literature reports mainly periprocedural problems.