Publications by authors named "Tokiya Ishida"

Background: Road traffic accidents are a major healthcare concern worldwide. To improve outcomes for patients injured in motor vehicle crashes, it is crucial to understand the factors associated with mortality and anatomically specific injury severity. Seat position is one of the possible determinants of road traffic injury fatality; however, evidence regarding which seat positions are linked to impaired survival outcomes and anatomically severe injuries remains scarce.

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  • - The Ohta Nishinouchi Hospital established a trauma protocol in 2013 aimed at improving outcomes for patients with severe trunk trauma, but its effectiveness had not been thoroughly evaluated until this study.
  • - The study analyzed data from 4,558 trauma patients treated between 2004 and 2019, using interrupted time-series analysis (ITSA) to assess in-hospital mortality rates before and after the protocol implementation.
  • - While ITSA showed no significant change in mortality rates, logistic regression analysis indicated that the protocol likely contributed to a reduction in in-hospital deaths, suggesting a more detailed analysis method is needed for future assessments.
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  • A pericardial drainage catheter can sometimes move into the right main pulmonary artery, which is a rare and serious complication.
  • This issue might arise when draining fluid from the pericardial space, especially if symptoms of cardiac tamponade (pressure on the heart) continue despite treatment.
  • If a lot of thick, bloody fluid is removed during the procedure, it raises the risk of this migration and potential life-threatening consequences.
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  • - The study focused on identifying risk factors for COVID-19 deterioration in unvaccinated individuals under 65 years old during Japan's fifth wave, as many cases occurred in this demographic.
  • - Researchers analyzed data from 1,675 patients in Fukushima and created predictive scores to estimate deterioration risk using logistic regression, highlighting significant factors like age, body temperature, oxygen saturation, and comorbidities (diabetes, obesity).
  • - The findings indicated that 8.6% of patients experienced deterioration, with predictors including older age, male gender, and various health issues; two risk scores were developed, DOATS and DOAT, to assess patient risk.
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  • A study was conducted to evaluate the efficacy of molnupiravir in hospitalized patients with mild-to-moderate COVID-19 during the Omicron variant surge in Fukushima, Japan, by comparing outcomes between those who used the drug and those who did not.
  • After matching molnupiravir users with non-users based on similar characteristics, results showed that the clinical deterioration rate was significantly lower for users (3.90%) compared to non-users (8.40%).
  • Multivariate analysis indicated that treatment with molnupiravir independently reduced the risk of deterioration in COVID-19 patients after hospitalization during the Omicron variant phase.
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  • In cases where transcatheter arterial embolization (TAE) of pseudoaneurysms is challenging due to small or tortuous arteries, n-butyl-2-cyanoacrylate (NBCA) is often used, but it poses risks of uncontrolled embolization.
  • Imipenem/cilastatin sodium (IPM/CS) presents a potential alternative for TAE, especially for traumatic pseudoaneurysms, although its use had not been documented prior to this case.
  • In a reported case, a 51-year-old man who suffered traumatic injuries underwent successful TAE using IPM/CS and microspheres, which resolved his refractory pelvic pseudoaneurysm without leading to rebleeding or
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Background: Nonoperative management (NOM) has become a standard strategy for hemodynamically stable patients with blunt splenic injury; however, delayed rupture of splenic pseudoaneurysm (SPA) is a serious complication of NOM. In medical literature, data regarding the long-term incidence of SPA are scarce, and the appropriate timing for performing follow-up contrast-enhanced computed tomography (CT) has not yet been reported. This study aimed to elucidate the long-term incidence and timing of SPA formation after blunt splenic injury in patients treated with NOM.

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  • - The study assessed the effectiveness of the monoclonal antibody treatment casirivimab-imdevimab for mild-to-moderate COVID-19 patients during the Delta variant surge in Fukushima, Japan, enrolling 949 patients.
  • - Casirivimab-imdevimab users were generally older and had higher rates of health issues like obesity, hypertension, and higher body temperatures compared to non-users.
  • - The findings show that receiving casirivimab-imdevimab significantly reduced the risk of clinical deterioration in hospitalized patients, highlighting its potential benefit during COVID-19 hospitalization (odds ratio 0.448).
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  • Postpartum hemorrhage is a significant risk during delivery, being the leading cause of maternal deaths worldwide, especially in high-risk patients.
  • The text discusses two specific cases of high-risk patients who underwent successful cesarean sections with a technique called resuscitative endovascular balloon occlusion of the aorta to manage potential massive bleeding.
  • In both cases, the patients had issues related to the placenta and were monitored closely; they both experienced natural placental resorption and were discharged without major complications five days after delivery.*
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Trial Design: This investigator-initiated, single-center, open-label, parallel-group, randomized-controlled pilot study was designed to compare the intraoperative fluid balance and perioperative complications in patients undergoing hepato-biliary-pancreatic surgery with or without stroke volume variation (SVV)-guided fluid management.

Methods: Patients who were aged >18 years and underwent elective major hepato-biliary-pancreatic surgery between June 30, 2015, and August 31, 2016 at our center were randomly assigned to receive SVV-guided or conventional fluid therapy. The intervention group used SVV to determine the patients' volume status.

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A 76-year-old man who had been bathing in a hot spring was taken to the hospital in a coma. PCR assay performed on the eschar revealed a serotype Hirano/Kuroki of . Coexisted heatstroke superimposed on multiple underlying risk factors likely led to a fatal clinical course.

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Background: Published reports regarding the use of veno-venous extracorporeal membrane oxygenation (V-V ECMO) for massive hemoptysis following a thoracic injury are still scarce.

Case Presentation: A 34-year-old man developed massive hemoptysis from the right lung after a 2 m fall and being compressed with an iron pipe weighing 500 kg. He was immediately intubated using a double-lumen tube, and one-lung ventilation was started.

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  • EndoVascular and Hybrid Trauma Management (EVTM) has been introduced for severe pelvic ring injuries, employing techniques like Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA) to manage hemorrhage, though data on its effectiveness is limited.
  • A study of 72 trauma patients with severe pelvic injuries found that most had blunt traumas, with traffic accidents being the most common cause, and REBOA was primarily used in the highest zone of aortic occlusion (zone 1).
  • The overall mortality rate was noted to be 54.2%, with early mortality at 44.4%, influenced by various factors such as pH levels and blood pressure, although these
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Background: Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA) may improve Systolic Blood Pressure (SBP) in hypovolemic shock. It has, however, not been studied in patients with impending traumatic cardiac arrest (ITCA). We aimed to study the feasibility and clinical outcome of REBOA in patients with ITCA using data from the ABOTrauma Registry.

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Background: Commencement of a new academic cycle is presumed to be associated with poor patient outcomes. However, supportive evidence is limited for trauma patients treated in under-resourced hospitals, especially those who require specialized interventions and with little physiological reserve. We examined whether a new academic cycle affects the survival outcomes of injured patients in a typical Japanese teaching hospital.

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Background: Resuscitative endovascular balloon occlusion of the aorta (REBOA) has been used in refractory hemorrhagic shock patients. Since the optimal timing of arterial access remains unclear, we evaluated the preocclusion status of patients, and elapsed time from the arrival to the hospital is associated with the survival outcomes in the REBOA patients.

Methods: From August 2011 to December 2016, The Diagnostic and Interventional Radiology in Emergency, Critical care and Trauma-Intra-Aortic Balloon Occlusion (DIRECT-IABO) investigators registered refractory hemorrhagic shock patients undergoing REBOA from 23 hospitals in Japan.

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Background: Clostridium septicum-infected aortic aneurysm is a fatal and rare disease. We present a fatal case of C. septicum-infected aortic aneurysm and a pertinent literature review with treatment suggestions for reducing mortality rates.

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Background: Resuscitative endovascular balloon occlusion of the aorta (REBOA) performed by emergency physicians has been gaining acceptance as a less invasive technique than resuscitative thoracotomy.

Objective: To evaluate access-related complications and duration of occlusions during REBOA.

Methods: Patients with haemorrhagic shock requiring REBOA, from 18 hospitals in Japan, included in the DIRECT-IABO Registry were studied.

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Background: Because most community hospitals in Japan do not maintain 24-h availability of in-house anesthesiologists, surgeons, and interventional radiologists, staffing dramatically declines during off hours. It is unclear whether, in such under-resourced hospitals, trauma patients presenting during off hours and requiring subspecialty intervention have worse outcomes than those who present during business hours.

Methods: This was a retrospective cohort study at a community hospital in Japan.

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Anaerobiospirillum succiniciproducens is rarely associated with bacteremia but results in significant mortality. Almost all reported bacteremia cases have occurred in immunocompromised hosts, such as those with alcoholic liver disease, atherosclerosis, recent surgery, malignancies, or acquired immunodeficiency syndrome. We describe here, to our knowledge, the first clinical evidence for A succiniciproducens bacteremia in a healthy man.

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