Publications by authors named "Tingbo Liang"
Clinical experience in liver transplantation from an organ transplantation center in China.
Hepatobiliary Pancreat Dis Int
November 2002
Objective: To sum up the experience in liver transplantation in a period of ten years at a single center.
Methods: We retrospectively reviewed the clinical records of 120 patients receiving liver transplantation from April 1993 to October 2002. The patients' clinical characteristics, surgical techniques, complications and survival were compared in the phases of 1993-1997 (phase I), 1999 (phase II), and 2000-2002 (phase III).
Orthotopic liver transplantation in treatment of 77 patients with end-stage hepatic disease.
Hepatobiliary Pancreat Dis Int
February 2002
Objective: To summarize the experience of human orthotopic liver transplantation (OLTx) in treatment of patients with end-stage hepatic disease and their perioperative management.
Methods: A retrospective analysis was made on OLTx performed in 77 patients from April 1993 to September 2001 in our department included combined liver-kidney transplantation (6 patients) and living related liver transplantation (2). Among them, 76 were adults and 1 was infant (67 males and 10 females).
Primary liver cancer in the elderly: report of 125 cases.
Hepatobiliary Pancreat Dis Int
February 2003
Objectives: To understand the characteristics of primary liver cancer (PLC) in the elderly and summarize the experience in treatment of such patients.
Methods: The clinical data of PLC in the elderly group (>/=60 years, 125 patients) and the young group (
Results: In the elderly group, 64 patients were found HBsAg positive, 39 patients small PLC, 24 large PLC, 15 tumor emboli in the portal vein, 86 AFP positive, and 34 hepatectomy performed.
Expression of 4-1BB molecule on peripheral blood T cells in liver transplanted patients and its clinical implication.
Hepatobiliary Pancreat Dis Int
February 2003
Objective: To investigate the gene expression of 4-1BB in peripheral blood mononuclear cells (PBMCs) and its possible significance in clinical liver transplantation.
Methods: Reverse transcription-polymerase chain reaction (RT-PCR) was used to determine the gene expression of 4-1BB in PBMCs from 22 patients receiving liver transplantation, 13 patients with primary liver carcinoma (PLC), and 12 healthy controls. To determine whether 4-1BB molecule is also expressed on the surface of CD4+ and CD8+ T cell, flow cytometry was used to analyse the phenotype of T cell subsets from the blood of liver transplantation patients.
[Early diagnosis of pancreatic cancer is essential to improving the effect of treatment].
Zhonghua Wai Ke Za Zhi
May 2003
Article Synopsis
- The study aimed to examine how the tumor's TNM classification in pancreatic cancer relates to treatment outcomes and summarize the diagnostic and treatment experiences over a 10-year period.
- Researchers analyzed data from 321 pancreatic cancer patients, focusing on survival rates and radical resection success across different TNM stages.
- Findings showed that early-stage patients (stages I and II) had significantly higher rates of radical resection and better survival outcomes compared to those diagnosed at more advanced stages, highlighting the importance of early diagnosis.
Article Synopsis
- - The study looked at how certain substances, like TNF-alpha and IL-1beta, affect the lungs of rats after they have liver transplants of different sizes.
- - Researchers found that rats who had liver transplants had more TNF-alpha in their blood compared to those who didn't have surgery, especially in the group with a whole liver.
- - The team also discovered that some substances were present in all transplant groups but not in the sham (no surgery) group, showing that liver transplants can significantly impact the expression of these substances in the lungs.
[The role of IL-15 in the process of acute rejection in liver and heart transplantation in rats].
Zhonghua Wai Ke Za Zhi
January 2003
Objective: To study the real effect of IL-15, a kind of T lymphocyte activators which were derived from lymphocytes, on the acute rejection process in heart and liver transplantation in rats.
Methods: Male (body weight 200 - 250 g) 1A (RT1(a)) and LEW (RT1(l)) rats were selected as donors and recipients, respectively. Heterotopic heart transplantation (in abdomen) and orthotopic liver transplantation were performed as the acute rejection model group (experimental group); LEW (RT1(l))-->LEW (RT1(l)) as donors and recipients to establish isografts transplantation as the control group.
[Clinical analysis of different periods of liver transplantation at an organ transplantation centre].
Zhonghua Wai Ke Za Zhi
January 2003
Objective: To summarize our clinical experience in liver transplantation while considering the background in this field in China.
Methods: Ninety-five patients who had received liver transplantation from April 1993 to March 2002 were analyzed retrospectively. Three periods were defined objectively as period I (1993 - 1997), II (1999) and III (2000 - 2002).
[Vascular complications after orthotopic liver transplantation].
Zhejiang Da Xue Xue Bao Yi Xue Ban
April 2003
Background: The molecular mechanism of small-for-size graft injury remains unclear. The aim of this study is to investigate the gene expression pattern of acute phase response in relation to graft size in a rat-liver transplantation model.
Methods: A rat orthotopic liver transplantation model using 30%, 50%, and whole grafts was used.
Objective: To investigate the degree and mechanism of hepatic sinusoidal injury in different graft sizes in right lobe live donor liver transplantation (LDLT).
Summary Background Data: Liver grafts from living donors are likely to be small-for-size for adult recipients. Graft injury after reperfusion is common, but the mechanism and degree of injury remain unclear.
[Lamivudine as prophylaxis against hepatitis B virus reinfection following orthotopic liver transplantation].
Zhonghua Yi Xue Za Zhi
April 2002
Objective: To discuss the effect of lamivudine as prophylaxis against hepatitis B virus (HBV) reinfection following orthotopic liver transplantation (OLT).
Methods: 40 patients with HBV-related diseases received lamivudine, 100 mg/day, as prophylaxis against HBV reinfection after OLT. Hepatitis B serum markers, HBsAg, HBeAg, HBcAb-IgM, and HBcAg were detected every 2 weeks by immunohistochemistry.
[Orthotopic liver transplantation for end-stage liver diseases in 71 cases].
Zhonghua Gan Zang Bing Za Zhi
February 2002
Objective: To assess the role of orthotopic liver transplantation (OLT) in the treatment of end-stage liver diseases and to discuss the experience of the operation.
Methods: Retrospective analysis of clinical data of 71 cases of liver transplantation was performed in our hospital from April 1993 to August 2001.
Results: One year survival rate of recipients with benign hepatic disease was over 75%.