Publications by authors named "Ting-Yu Nie"

Introduction: The hypertriglyceridemia-waist (HTGW) phenotype is a prevalent risk factor for cardiovascular diseases and obstructive sleep apnea (OSA). However, the impactof the HTGW phenotype on the simultaneous occurrence of OSA and cardiovascular diseases remains unexplored. This study aimed to determine whether the HTGW phenotype elevates the incidence of major adverse cardiovascular events (MACE) in patients with OSA, such as hospitalization for unstable angina and heart failure, myocardial infarction, and cardiovascular death, in patients with OSA.

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Background: The rising rates of obstructive sleep apnea (OSA) and frailty among older adults are linked to higher mortality rates. Depression merges as a critical determinant associated with both OSA and frailty. This study investigates the impact of depression on the risk of developing frailty in older adults diagnosed with OSA.

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Background: Previous studies have demonstrated a significant correlation between obstructive sleep apnea (OSA) and frailty. However, the association of mean pulse oxygen saturation (MSpO) with frailty among OSA patients remains unconfirmed. This study aimed to explore this potential association using data from a multicenter, prospective cohort.

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Article Synopsis
  • The study explored gut microbiota differences in patients with severe obstructive sleep apnea (OSA) and how these changes occur after three months of CPAP treatment.
  • Using various analysis methods, the research found specific bacterial populations significantly altered in OSA patients compared to healthy controls and showed correlations between certain gut bacteria and blood pressure levels.
  • The findings indicate that gut microbiota and metabolic pathways are notably different in OSA patients, and that CPAP therapy can meaningfully impact both gut bacteria composition and overall health.
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Background: The concomitant rise in the prevalence of obstructive sleep apnea (OSA) and frailty among the elderly population has been linked to an increase in mortality rates. Despite continuous positive airway pressure (CPAP) being the gold standard treatment for OSA, its impact on incident frailty remains inadequately explored.

Methods: In this cohort study, we analyzed data from 1290 patients diagnosed with OSA, aged 60 years and older.

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