Limited generalizability and high risk of bias in multivariable models predicting conversion risk from mild cognitive impairment to dementia: A systematic review.

Prediction models have been developed to identify mild cognitive impairment (MCI) cases likely to convert to dementia. This systematic review summarizes multi-source prediction models for MCI to dementia conversion. PubMed and Embase were searched for model development and validation studies from inception up to January 18 2024.

Prognostic Information on Progression to Dementia: Quantification of the Impact on Quality of Life.

Background: The increasing interest in early identification of people at risk of developing dementia, has led to the development of numerous models aimed at estimating the likelihood of progression from mild cognitive impairment (MCI) to dementia. It is important to study both the need for and possible outcomes related with such prediction models, including the impact of risk predictions on perceived quality of life (QoL).

Objective: This study aimed to quantify the impact that receiving a risk prediction on progression from MCI to dementia has on QoL.

Bladder EpiCheck urine test in the follow-up of NMIBC: a cost analysis.

Purpose: In the Netherlands yearly more than 5000 patients are diagnosed with non-muscle invasive bladder cancer (NMIBC). With a specificity of 88.0% and a negative predictive value (NPV) for high grade NMIBC of 99.