Publications by authors named "Tiago C Tomas"
The tumor microenvironment is crucial in tumourigenesis, response to therapy, and elimination of tumor cells. Tumor-infiltrating lymphocytes (TILs) promote the host immune response and are associated with a better prognosis in colorectal cancer (CRC). This multicentric retrospective study evaluated the relationship between the presence and intensity of TILs and survival outcomes.
View Article and Find Full Text PDFBackground: Perioperative fluorouracil plus leucovorin, oxaliplatin, and docetaxel (FLOT) improves prognosis in locally advanced gastric cancer (LAGC). Neutrophil-to-lymphocyte (NLR), lymphocyte-to-monocyte (LMR), and platelet-to-lymphocyte (PLR) ratios are prognostic biomarkers but not predictive factors.
Aim: To assess blood ratios' (NLR, LMR and PLR) potential predictive response to FLOT and survival outcomes in resectable LAGC patients.
Article Synopsis
- Increasing cancer survival rates have led to more cancer patients being admitted to ICUs, prompting a need to assess their outcomes compared to non-cancer patients.
- A study analyzed 236 oncological patients admitted to a polyvalent ICU from 2013 to 2017, finding that hematological patients experienced worse outcomes, longer ICU stays, and higher treatment requirements than solid tumor patients.
- The study concluded that the SAPS II and APACHE II scores effectively predict mortality in cancer patients, with a survival rate of 48% at six months being higher than previously reported.