Publications by authors named "Thiago Nascimento do Prado"

Objective: To evaluate the completeness of COVID-19 notification form data on the Indigenous population living in the state of Espírito Santo, Brazil, in 2020.

Methods: This was a descriptive cross-sectional study carried out on COVID-19 notification data on the Indigenous population living in Espírito Santo in 2020. The scores used to assess completeness were: excellent (>95,0%), good (91,0%-95,0%), regular (81,0%-90,0%), poor (50,0%-80,0%) and very poor (<50,0%).

View Article and Find Full Text PDF

Background: Monotherapy with the drug isoniazid (INH) was for a long time the main therapeutic regimen used for tuberculosis preventive treatment (TPT). Research is progressing into the use of new therapeutic regimens that provide more complete TPT. The objective was to analyze the completion and safety of TPT with the drug INH in the form of 300 mg tablets.

View Article and Find Full Text PDF

This study aimed to analyze the cost-effectiveness of three tuberculosis (TB) antigen-based skin tests (TBST) (Diaskintest, C-TST, and Cy-TB) and QFT-Plus for TB infection diagnosis compared to the current standard of care, PPD Rt-23 tuberculin skin test (TST), among healthcare workers in Brazil. A state-transition Markov model was employed, simulating a cohort of healthcare workers (five annual cycles) for testing and treating TB infection with three months of weekly doses of rifapentine and isoniazid (3HP) under the Brazilian public health system perspective. Effects (TB disease averted) and costs for screening and treating TB infection were discounted at 5%.

View Article and Find Full Text PDF

Objective: To estimate prevalence of the full vaccination schedule for children 12 to 24 months old and to analyze associated factors.

Methods: Survey with cluster sampling carried out in Vitória, Espírito Santo, Brazil, between December 16, 2020, and January 4, 2021. Children born in Vitória in 2017 and 2018 were included.

View Article and Find Full Text PDF

Introduction: It is essential to strengthen the treatment of latent tuberculosis infection (LTBI) to break the chain of transmission. The drug used worldwide for the treatment of LTBI is Isoniazid. A clinical trial conducted in Brazil has demonstrated the bioequivalence of Isoniazid in the 300 mg formulation with 3 tablets in the 100 mg formulation.

View Article and Find Full Text PDF

We assessed the effectiveness of food vouchers as a social protection strategy to enhance the adherence to tuberculosis treatment in health-care facilities in Brazil between 2014 and 2017. A cluster-randomized controlled trial was performed in four Brazilian capital cities. A total of 774 adults with newly diagnosed pulmonary tuberculosis were included in this study.

View Article and Find Full Text PDF

Objectives: to analyze government social initiatives aimed at people with tuberculosis and the possibilities of access to government social programs and income transfers through the perception of tuberculosis program managers.

Methods: descriptive, qualitative study with 19 managers from Belém, Recife, Campo Grande, and Rio de Janeiro, Brazil. Thematic content analysis was used.

View Article and Find Full Text PDF

Background: Non-compliance with latent tuberculosis infection (LTBI) treatment is a reality. The objective of this study was to develop and validate an mobile device application for monitoring the treatment of LTBI.

Methods: We defined the requirements, elaborated on the application's conceptual map, generated implementation and prototyping alternatives, and validated content.

View Article and Find Full Text PDF

Background: The provision of care and monitoring of health are essential for indigenous Venezuelans from the Warao ethnic group, who are at risk of decimation.

Objective: Analyze a Local Action Plan (LAP) to promote access to the health system of indigenous Venezuelans from the Warao ethnic group (IVWEG) in Manaus, Brazil.

Method: A mixed-methods study was performed.

View Article and Find Full Text PDF
Article Synopsis
  • The study analyzed the spread of yellow fever in Espírito Santo, Brazil, during the 2017 epidemic, focusing on its geographic and temporal distribution.
  • Using ArcGIS software, the research found an incidence rate of 4.85 cases per 100,000 people, with a case-fatality rate of 29.74%, affecting 34 out of 78 municipalities.
  • The analysis showed that yellow fever initially spread from municipalities near Minas Gerais and moved eastward, primarily affecting Central and Metropolitan regions rich in Atlantic Forest, indicating a pattern of contagion.
View Article and Find Full Text PDF

Objective: To evaluate the impact of catastrophic costs on unfavorable tuberculosis treatment outcomes.

Methods: This was a prospective cohort study, conducted in five Brazilian state capitals (Manaus, Recife, Vitória, Campo Grande and Porto Alegre) from June 2016 to July 2018. Logistic regression was used to calculate the odds ratio (OR) and 95% confidence intervals (95%CI).

View Article and Find Full Text PDF

Objectives: Healthcare workers (HCWs) have a high risk of acquiring tuberculosis infection (TBI). However, annual testing is resource-consuming. We aimed to develop a predictive model to identify HCWs best targeted for TBI screening.

View Article and Find Full Text PDF

Background: Migrants are a high priority group for TB control measures due to their high exposure to risk factors such as poverty and social vulnerability. The study aimed to identify factors associated with latent TB among international migrants living in four Brazilian state capitals. This was a cross-sectional study conducted in September and October 2020 in a sample of 903 international migrants living in four Brazilian state capitals: Boa Vista/RR (458), Manaus/AM (136), São Paulo/SP (257), and Curitiba/PR (52).

View Article and Find Full Text PDF

Objectives: to develop an ICNP® terminology subset to care for people with tuberculosis.

Methods: a methodological research that followed the following steps: identification and validation of empirical indicators of altered needs relevant to people with tuberculosis based on literature; cross-mapping of the empirical indicators of altered needs identified with ICNP® 2017 terms; construction of nursing diagnoses/outcomes and interventions; assessment of relevance of nursing diagnoses /outcomes and interventions and ICNP® terminology subset structuring.

Results: an ICNP® terminology subset was developed to care for people with tuberculosis with 51 diagnoses/outcomes and 264 nursing interventions, assessed by nurses from Primary Health Care and structured according to Wanda Horta's Theory of Basic Human Needs.

View Article and Find Full Text PDF
Article Synopsis
  • The study aimed to identify factors contributing to the likelihood of tuberculosis treatment discontinuation among patients in an outpatient setting in Brazil.
  • Researchers followed 148 patients over seven years and found that smoking, drug use, and a high abandonment risk score significantly increased the chances of discontinuing treatment.
  • The results indicated that smoking and undergoing retreatment were key independent risk factors for treatment abandonment, highlighting the importance of targeting patients at higher risk to improve treatment adherence.
View Article and Find Full Text PDF

Objective: To assess the association between tuberculosis determinants and performance of directly observed treatment (DOT) under different levels of Family Health Strategy (FHS) coverage in Brazil.

Methods: This was a cross-sectional study using data on tuberculosis cases notified between 2014 and 2016 on the Notifiable Health Conditions Information System, as well as data on FHS coverage in the municipality of residence. Logistic regression was used.

View Article and Find Full Text PDF

Objectives: to develop and validate management tools for the systematization of nursing care for children with pressure injuries.

Methods: methodological study in which the focus group technique was used for validation of tools in three different groups of 17 nurses. Conducted in April and May 2018 at a large pediatric hospital.

View Article and Find Full Text PDF

Objective to describe the completeness of data on yellow fever notification forms in the municipalities of the state of Espírito Santo, Brazil, in 2017. Methods this is a descriptive ecological study with data from the Notifiable Health Conditions Information System (SINAN); form completeness was categorized as poor (<70.0%), regular (70-89.

View Article and Find Full Text PDF

Objective: to analyze the spatial distribution of syphilis cases in pregnancy and congenital syphilis cases, from 2011 to 2018.

Methods: this was an ecological study applying spatial analysis of syphilis cases in pregnancy and congenital syphilis reported on the Notifiable Diseases Information System; TerraView 4.2.

View Article and Find Full Text PDF

In 2015, Brazil faced a Zika virus epidemic that spread to other countries in the world. As a result, recommendations regarding reporting criteria for congenital Zika syndrome (CZS) were issued in the form of protocols. The frequent changes in these recommendations may have affected clinical management and the access to post-diagnostic support by children who were affected by CZS, but who ended up not being identified.

View Article and Find Full Text PDF

Objective: Describe the sociodemographic profile of mothers of children with congenital Zika syndrome.

Methods: This is a descriptive, cross-sectional, quantitative study. The 39 mothers of live born babies among the cases notified in 2015 and 2016 with confirmed diagnosis of congenital Zika syndrome in the state of Espírito Santo, Brazil, were invited to participate.

View Article and Find Full Text PDF

Objective: to analyze factors associated with cure when treating tuberculosis (TB) in the state of Rio de Janeiro, Brazil, from 2011 to 2014.

Methods: this was a cross-sectional study with data from the Notifiable Diseases Information System (SINAN); logistic regression was used for data analysis.

Results: of the 57,142 cases reported, 49,691 (86.

View Article and Find Full Text PDF