L.: Analysis of Chemical Profile and Cytotoxic Action on Tumor (HeLa) and Non-Tumor Cells (NIH/3T3).

This study analyzed the antiproliferative potential of L. leaf extracts against cervical cancer and non-cancerous cell lines. The extracts were prepared by maceration using hexane (EUH), dichloromethane (EUD), and ethyl acetate (EUA).

Chitosan nanocomposite containing rotenoids: an alternative bioinsecticidal approach for the management of .

Climate change has intensified the proliferation of disease vectors, such as , the primary transmitter of dengue, chikungunya, and zika viruses. Although the two recently licensed dengue vaccines represent a significant advancement, vector management remains the primary strategy for preventing these urban arboviruses. In this context, the development of pesticides that offer safer alternatives for the environment and human health has become urgent.

The Development and Characterization of an Andiroba Oil-Based Nanoemulsion (, Aubl.): Insights into Its Physico-Chemical Features and In Vitro Potential Healing Effects.

Andiroba oil, extracted from seeds, possesses therapeutic properties including anti-inflammatory and wound healing effects. This study aimed to develop and characterize a nanoemulsion formulation containing andiroba oil (NeAnd) and to evaluate its cytotoxicity and wound healing potential in vitro. : The oil was evaluated for acidity, antioxidant activity, and fatty acid composition.

Eugenia brasiliensis: Analysis of the Chemical Profile and Evaluation of Cytotoxic Potential.

This work evaluated the antiproliferative potential of Eugenia brasiliensis leaf extracts against the HeLa cervical cancer cell line. The extracts were prepared by maceration using hexane (EBH), dichloromethane (EBD), and ethyl acetate (EBAE), and they were evaluated for their antiproliferative potential through a 3-4,5-dimethyl-thiazol-2-yl-2,5-diphenyltetrazoliumbromide (MTT) assay in the cervical cancer cell culture (HeLa cell line) and a non-cancer cell line (NIH-3T3). EBH, EBD, and EBAE were cytotoxic in HeLa cells, with 50% inhibition concentration (IC) = 97.

Antimycobacterial and nitric oxide production inhibitory activities of limonoids isolated from Trichilia lepidota subsp. schumanniana (Harms) T.D.Penn.

Six previously undescribed intact limonoids together with four known compounds were isolated from the seeds of Trichilia lepidota subsp. schumanniana (Harms) T.D.

Antihypertensive Activity of the Alkaloid Aspidocarpine in Normotensive Wistar Rats.

The alkaloid Aspidocarpine was isolated from the bark of Aspidosperma desmanthum. Its structure was elucidated by the spectral data of 1H and 13C-NMR (1D and 2D) and high-resolution mass spectrometry (HRESIMS). The antihypertensive activity was investigated by intravenous infusion in Wistar rats.

Chemical Compounds and Biologic Activities: A Review of Genus.

The genus P. Browne, which belongs to the Meliaceae family, has eighteen species. Trees of this genus are of economic interest due to wood quality, as well as being the focus of studies because of relevant biologic activities as in other Meliaceae species.