Publications by authors named "Tehreem Haider"
Daidzein ameliorates experimental traumatic brain injury-induced neurological symptoms by suppressing oxidative stress and apoptosis.
J Biochem Mol Toxicol
November 2024
Article Synopsis
- Traumatic brain injury (TBI) leads to neurological deficits and oxidative stress, prompting research into the neuroprotective effects of Daidzein, a phytoestrogen.
- In vitro studies with HT-22 cells showed that Daidzein improved cell survival and reduced harmful nitric oxide production, while in vivo tests using three doses of Daidzein demonstrated significant improvements in neurological functions and anxiety behaviors.
- Molecular analysis indicated that Daidzein enhances antioxidant defenses and reduces markers of cell damage and apoptosis, showing promise as a treatment for TBI-related complications.