Endovascular treatment of vertebral artery ostial stenosis with second generation drug-eluting coronary stents: Long-term follow up.

Background And Purpose: To evaluate the patency and clinical outcomes of drug-eluting stents (DES) in patients with symptomatic and significant vertebral artery ostial stenosis (VAOS).

Methods: This single-center, retrospective observational study included 31 patients (21 males, 10 females; mean age: 64 ± 10.56 years) who underwent DES placement for severe (>70 %) symptomatic VAOS in our institution between 2013 and 2023.

Unilateral facial nerve paralysis following prolonged weekly paclitaxel therapy: a rare case of cranial neurotoxicity with diagnostic challenges.

Background: Paclitaxel is a widely used chemotherapeutic agent for the treatment of breast cancer. While peripheral neuropathy is a well-recognized dose-limiting toxicity of paclitaxel, cranial nerve involvement remains exceptionally rare. We report a case of unilateral facial nerve palsy in a breast cancer patient receiving standard-dose paclitaxel therapy, highlighting the diagnostic challenges in distinguishing drug-induced neurotoxicity from other aetiologies.

The effect of spasticity severity on peripheral muscle oxygenation in hemiparetic stroke patients: a cross-sectional study.

Background: Spasticity-induced muscle changes affect structure and metabolism. Little is known about the effect of stroke-related muscle changes on peripheral muscle oxygenation.

Objective: To investigate the effect of spasticity severity on peripheral muscle oxygenation in patients with hemiparetic stroke.

The Influence of Smoking and Systemic Inflammation on Carotid Artery Disease: A Cross-Sectional Analysis of Stenosis, Plaque Surface Characteristics.

The role of inflammation in carotid plaque formation and instability has been highlighted in recent studies. We assessed the significance of smoking status on systemic inflammation and their relationships with carotid stenosis and carotid plaque surface characteristics. A total of 822 patients diagnosed with carotid artery stenosis were recruited and evaluated with systemic inflammation indices according to smoking status.

Diagnostic Transitions from Primary Psychiatric Disorders to Underlying Medical Conditions: A 5-Year Retrospective Survey from a University Hospital Sample.

Background: Undiagnosed underlying medical conditions can cause many patients to be followed, for years, by a diagnosis of a primary psychiatric disorder and to receive inappropriate treatment. The aim of this study was to determine the prevalence of patients initially diagnosed with a primary psychiatric disorder but whose symptoms were later attributed to medical conditions. These patients' initial and final diagnoses were also examined.

Predictive Value of Supraventricular Short Runs for New-Onset Atrial Fibrillation in Patients with Ischemic Stroke.

Background: The clinical importance of supraventricular run (SVR) is uncertain in the management of patients with previous cerebrovascular events. We aim to evaluate the role of SVRs in the development of future atrial fibrillation (AF) in patients diagnosed with ischemic stroke.

Methods: We retrospectively evaluated patients who underwent 24-h Holter monitoring for the evaluation of possible AF after ischemic cerebrovascular events.

QT interval alterations in epilepsy: A thorough investigation between epilepsy subtypes.

Objectives: Cardiac disturbances and rhythm abnormalities which potentially lead sudden unexpected death in epilepsy, have been extensively studied in focal epilepsies. However, studies including generalized epilepsies are scarce and it is not clear whether electrocardiogram parameters reflecting vulnerability to ventricular arrhythmias differ between these groups.

Methods: Medical records of patients who were followed in epilepsy department of a tertiary center between October 2015 and September 2016 were retrospectively reviewed.

Novel RETREG1 (FAM134B) founder allele is linked to HSAN2B and renal disease in a Turkish family.

Hereditary sensory and autonomic neuropathy type 2B (HSAN2B) is a rare autosomal recessive peripheral neuropathy caused by biallelic variants in RETREG1 (formerly FAM134B). HSAN2B is characterized by sensory impairment resulting in skin ulcerations, amputations, and osteomyelitis as well as variable weakness, spasticity, and autonomic dysfunction. Here, we report four affected individuals with recurrent osteomyelitis, ulceration, and amputation of hands and feet, sensory neuropathy, hyperhidrosis, urinary incontinence, and renal failure from a family without any known shared parental ancestry.

Posterior Circulation Alberta Stroke Program Early Computed Tomography Score (pc-ASPECT) for the Evaluation of Cerebellar Infarcts.

Background: Patients with cerebellar ischemic stroke may be misdiagnosed and may exhibit a delayed time to acute stroke treatment compared with patients with anterior circulation ischemic stroke. The posterior circulation Alberta stroke program early computed tomography score (pc-ASPECT) score has been used to evaluate hyperacute stroke, much as the ASPECT in anterior circulation stroke recently. Our main objective was to evaluate the associations of the clinical and etiological characteristics of ischemic cerebellar infarction patients on admission with their pc-ASPECT scores, as well as the correlations of the pc-ASPECT score with morbidity and mortality rates.

Headache features of cerebellar ischemic strokes: Clinical and radiological-experiences of a single center.

The prevalence of headache in stroke has been reported between 8% and 34%. Determining the prevalence, features, and effects on prognosis of cerebellar ischemic strokes that presented with headache solely and/or with other cerebellar signs were the aims of our study.All patients diagnosed with cerebellar ischemia were included.