Clove Oil-Based Nanoemulsion Containing Amphotericin B as a Therapeutic Approach to Combat Fungal Infections.

Candidiasis, primarily caused by , and sporotrichosis, mainly caused by , are skin fungal infections that pose serious threats to global health. The is a great concern in immunocompromised individuals, and while cause sporotrichosis, an infection commonly found in cats, this disease can be transmitted to humans through scratches or bites. Existing treatments for these fungal infections often cause problems related to resistance and significant side effects.

Graphene quantum dots for breast cancer treatment.

Introduction: Graphene quantum dots (GQDs) have emerged as promising nanomaterials for controlled drug delivery and breast cancer treatment, thanks to their biocompatibility, large surface area, and tunable optical properties.

Areas Covered: This review explores their synthesis, characterization, and application in breast cancer therapy, highlighting their role as drug carriers and theranostic platforms.

Expert Opinion: Some studies suggest that the efficiency of drug release depends on factors such as pH, mechanical stress, light exposure and temperature, which vary according to the type of nanocarrier and the experimental conditions.

Nanotechnology-Driven Strategy Against SARS-CoV-2: Pluronic F127-Based Nanomicelles with or Without Atazanavir Reduce Viral Replication in Calu-3 Cells.

Despite extensive efforts, no highly effective antiviral molecule exists for treating moderate and severe COVID-19. Nanotechnology has emerged as a promising approach for developing novel drug delivery systems to enhance antiviral efficacy. Among these, polymeric nanomicelles improve the solubility, bioavailability, and cellular uptake of therapeutic agents.

Use of Nanocarriers Containing Antitrypanosomal Drugs for the Treatment of Chagas Disease.

Chagas disease, caused by the parasitic protozoan, is a neglected tropical disease (NTD) of significant incidence in Latin America. Transmission to humans and other mammals is mainly via the vector insect from the Reduviidae family, popularly known as the kissing bug. There are other transmission means, such as through congenital transmission, blood transfusions, organ transplantations, and the consumption of contaminated food.

Nanocarriers for siRNA Delivery Aimed at the Treatment of Melanoma: Systematic Review.

Melanoma is a malignant skin cancer type with a high lethality rate due to active metastasis. Among the risk factors for its development is exposure to ultraviolet radiation (UV) and phenotypical characteristics such as clear skin and eyes. Given the difficulties of the conventional therapy, the high cost of the treatment and the low bioavailability of drugs, it is important to develop new therapeutic methods to circumvent this situation.

Trends in Nanomedicines for Cancer Treatment.

Background: Cancer is characterized by abnormal cell growth and considered one of the leading causes of death around the world. Pharmaceutical Nanotechnology has been extensively studied for the optimization of cancer treatment.

Objective: Comprehend the panorama of Pharmaceutical Nanotechnology in cancer treatment, through a survey about nanomedicines applied in clinical studies, approved for use and patented.

Trends in Nanotechnology for in vivo Cancer Diagnosis: Products and Patents.

Background: Cancer is a set of diseases formed by abnormal growth of cells leading to the formation of the tumor. The diagnosis can be made through symptoms' evaluation or imaging tests, however, the techniques are limited and the tumor detection may be late. Thus, pharmaceutical nanotechnology has emerged to optimize the cancer diagnosis through nanostructured contrast agent's development.