Resveratrol conjugated with silica nanoparticles used for in vitro bovine oocytes maturation.

The objective was to evaluate the use of resveratrol conjugated with silica nanoparticles during the maturation of bovine oocytes. The oocytes were divided into the following treatment groups during the maturation process: control ( = 159), resveratrol 0.5 μM ( = 158), resveratrol 1 μM ( = 155), nanoparticles conjugated with 0.

Exploring cellulose-derived esters/curcumin materials: Synthesis, characterization, and biological assay in zebrafish model.

A crucial challenge for science is to transform agricultural production waste into high-value-added materials suitable for multiple applications, such as in the construction of electronic devices or the medical field, such as scaffolds for tissue engineering or controlled drug release. Thus, we used polymers derived from cellulose from corn husks, from local agricultural production. In this study, we evaluated the physical-chemical and biological properties of polymeric films of cellulose acetate phthalate (CAP) and cellulose triacetate (CTA), and their blends with curcumin (CUR).

Zinc oxide nanoparticles functionalized with curcumin supplementation during in vitro embryo culture impaired in a concentration-dependent-manner blastocyst production in cattle.

This work investigated the effect of zinc oxide nanoparticles functionalized with curcumin (ZnO  + CUR) supplementation during the in vitro embryo culture (IVC) on the bovine in vitro embryo production, and the cellular antioxidant response. The cumulus-oocyte complexes (COCs) were matured, fertilized and then the presumptive zygotes were cultured in the medium in the absence (0 μM-control) or presence of different concentrations of ZnO  + CUR (3, 6 or 12 μM). After IVC, the embryos were destined either to assay intracellular ROS levels and mitochondrial membrane potential.

Embryotoxicity of silica nanoparticles in the drug delivery of domperidone in zebrafish.

Domperidone is a dopamine D2 receptor inhibitor that stimulates pituitary gonadotropins. It is usually associated with synthetic GnRHa to promote spawning in fish. However, the route of administration used, intramuscular injection, can be quite stressful.

Photoprotective activity of zirconia nanoparticles.

The increasing incidence of diseases caused by the harmful effects of UV radiation in skin, predominantly skin cancer, induce the search for more efficient photoprotector agents. Nowadays, titanium dioxide (TiO) and zinc oxide (ZnO) are the most widely used photoprotectors and therefore form the main components of commercially available sunscreens. Although the outstanding efficiency in absorbing and scattering UV radiation, mainly as nanoparticles, recent studies have raised concerns regarding the safe use of these nanoparticles, especially due to their high generation of reactive oxygen species (ROS).

PHBV-TiO mats prepared by electrospinning technique: Physico-chemical properties and cytocompatibility.

One of the most important challenges in tissue engineering research is the development of biomimetic materials. In this present study, we have investigated the effect of the titanium dioxide (TiO ) nanoparticles on the properties of electrospun mats of poly (hydroxybutyrate-co-3-hydroxyvalerate) (PHBV), to be used as scaffold. The morphology of electrospun fibers was observed by scanning electron microscopy (SEM).

Dynamic and structural correlations in nanocomposites of silica with modified surface and carboxylated nitrile rubber.

Distinct affinities between the organic and inorganic phases were observed in nanocomposites prepared through a colloidal route with carboxylated nitrile rubber and modified silica nanoparticles, which resulted in variable mechanical properties and improved thermal stability. Nanoparticles with modified surface affected the macromolecular arrangements of the elastomeric matrix, changing the final mechanical behavior of the nanocomposite, which could be predicted by the spin-lattice relaxation time measured by solid-state NMR. It was also possible to identify how each different nanoparticle affected the molecular dynamic of nanocomposite, correlating the dynamic-mechanical analysis with the NMR data of the saturated carbons of the elastomer.

Lead detection using micro/nanocrystalline boron-doped diamond by square-wave anodic stripping voltammetry.

Monitoring heavy metal ion levels in water is essential for human health and safety. Electroanalytical techniques have presented important features to detect toxic trace heavy metals in the environment due to their high sensitivity associated with their easy operational procedures. Square-wave voltammetry is a powerful electrochemical technique that may be applied to both electrokinetic and analytical measurements, and the analysis of the characteristic parameters of this technique also enables the mechanism and kinetic evaluation of the electrochemical process under study.