Quinazolinone-grafted polymers as novel insecticides: Synthesis, activity against Spodoptera littoralis, and environmental safety assessment.

Insecticides are crucial for crop protection against pests; research aims to develop effective and safe insecticides. This study aimed to evaluate 11 quinazolinone-based derivatives grafted with chitosan, polymethylmethacrylate, and carboxymethylcellulose against larvae of the cotton leafworm Spodoptera littoralis. The synthesized 2-hydrazinyl-3-phenylquinazolin-4(3H)-one (compound 2) and its grafted polymers were characterized via H NMR, XRD, FT-IR, and TGA analyses.

Insecticidal activity of some synthesized 1,3,4-oxadiazole derivatives grafted on chitosan and polymethylmethacrylate against the cotton leafworm Spodoptera littoralis.

To combat insect pests and vectors that are responsible for high losses in food and lives, insecticide discovery is of top priority. This study aimed to synthesize, characterize and investigate the insecticidal activity of 1,3,4-oxadiazole derivatives grafted on chitosan (CS) and modified polymethyl methacrylate (PMMA). 5-(pyridin-3-yl)-1,3,4-oxadiazole-2-thiol and 5-(pyridin-4-yl)-1,3,4-oxadiazole-2-thiol were respectively reacted with ethylchloroacetate and methyl-2-choloroacetoacetate.