Publications by authors named "Tapiwa Lundu"
Background: The inappropriate use of antimicrobials in poultry farming is associated with the emergence of antimicrobial-resistant Enterobacterales. This cross-sectional study aimed to identify various cefotaxime-resistant and β-lactamase-producing Enterobacterales and characterize their antimicrobial resistance profiles.
Methods: Pooled cloacal and meat samples collected from market-ready broiler chickens in Kitwe and Ndola districts of Zambia were screened for cefotaxime-resistant Enterobacterales.
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- * Our findings identified new or previously unclassified viruses, including murine adenovirus 4 and two new species from the paramyxovirus and picornavirus families.
- * The study highlights rodents as significant carriers for potential zoonotic viruses, which could pose risks to human health in the future.
Article Synopsis
- * A study in Zambia identified eighteen new species of bunyaviruses using a broad-spectrum RT-PCR method, along with RNA sequencing to analyze their genomes.
- * Combining RT-PCR and RNA sequencing revealed a rich diversity of bunyaviruses and provided insights into the ecology of mosquitoes that consume blood.
Article Synopsis
- Severe fever with thrombocytopenia syndrome virus (SFTSV) is a newly identified virus in East Asia, where its glycoproteins (GP) are crucial for the virus's ability to assemble in specific cellular compartments.
- The study reveals that SFTSV GP is essential for directing structural proteins like RNA-dependent RNA polymerase (L) and nucleocapsid protein (NP) to the ER-Golgi intermediate compartment (ERGIC) and Golgi complex, enabling proper viral assembly.
- Experiments show that while GP guides the localization of L, it does not influence NP's positioning, indicating that NP may require other interactions for its correct localization in infected cells.