Publications by authors named "Taejun Sim"
SFMBT2-Mediated Infiltration of Preadipocytes and TAMs in Prostate Cancer.
Cancers (Basel)
September 2020
Article Synopsis
- Infiltration of preadipocytes and tumor-associated macrophages (TAMs) into the prostate tumor microenvironment is influenced by the regulation of SFMBT2, which impacts cancer progression.
- Down-regulation of SFMBT2 results in increased levels of specific proteins (CXCL8, CCL2, CXCL10, and CCL20) that promote the infiltration of these cells, particularly in patients with higher Gleason scores.
- SFMBT2's regulatory role suggests it may be a promising target for therapy to reduce prostate cancer metastasis and could serve as a potential biomarker for the disease.