Unlocking the Potential of Extracellular Vesicles as the Next Generation Therapy: Challenges and Opportunities.

Background: Mesenchymal stem cells (MSCs) have undergone extensive investigation for their potential therapeutic applications, primarily attributed to their paracrine activity. Recently, researchers have been exploring the therapeutic potential of extracellular vesicles (EVs) released by MSCs.

Methods: MEDLINE/PubMed and Google scholar databases were used for the selection of literature.

The Rapid Development of Airway Organoids: A Direct Culture Strategy.

Introduction: The lung is a complex organ composed of numerous cell types. Exposure to air pollutants, cigarette smoke, bacteria, viruses, and many others may cause injury to the epithelial cells that line the conducting airways and alveoli. Organoids are the 3D self-organising structures grown from stem cells and generated from adult stem and progenitor cells.