Circle of Security-Parenting and Parent-Child Interaction Therapy-Toddler: A Qualitative Exploration of Parents' Perspectives.

Parent-Child Interaction Therapy-Toddler (PCIT-T) and Circle of Security-Parenting (COS-P) are two attachment-based early parenting programs with emerging evidence bases. Most of the research has, however, been quantitative in nature. Understanding caregiver perspectives and acceptability of the programs is therefore needed.

What constitutes pro-human papillomavirus vaccination videos on social media? Message characteristics, strategies, and theoretical constructs.

Videos are essential for promoting human papillomavirus (HPV) vaccinations across populations because videos encompass multiple message characteristics. To understand the patterns of message characteristics, strategies, and theoretical constructs embedded in videos of different types, we coded and analysed 38 variables from 56 videos across five types of pro-HPV vaccination videos (talking head, animation, produced-story, velfie, and mixed-type). We discovered that message characteristics such as redundancy, use of statistics, vividness, video quality, accuracy, authenticity, obtrusiveness, and doctor's recommendations varied across video types.

The structured practice approach: An innovation for clinical skills education.

In nursing curricula, it is vital that undergraduate nursing students learn specialist clinical skills within simulated laboratory settings and understand their application to practice. Along with the physical clinical skill, students must develop their critical thinking and clinical reasoning skills to understand when and why certain skills would be utilised, and what outcomes are predicted. There are many ways to facilitate learning within this setting, but there is little clear instruction for the educator tasked with d emonstrating within simulated clinical environments.

Motivational Interviewing and Case-Based Learning Approach Toward Tobacco Cessation Behavior Changes.

Health care professionals and health care students need effective skills to address the public health issue of tobacco use disorder. An accredited tobacco treatment specialist (TTS) program that includes case-based motivational interviewing (MI) instruction and role-playing with case-based tobacco scenarios, provides an opportunity to obtain or improve tobacco cessation skills. It is important for health care students to develop competency in MI as part of the evidence-based strategies used to assist individuals with tobacco cessation.

The role of child language ability and parental mentalization in early child dysregulation.

Dysregulation in early childhood is associated with increased vulnerability to psychopathology and poor psychosocial outcomes. While there is evidence that both child language ability and parental mentalization are associated with dysregulation in early childhood, there is little understanding of the relationships between these variables, and minimal research has been conducted in clinical samples. This study tested the association between child language ability (using the Mullens Scale of Early Learning) and child dysregulation (using the Child Behavior Checklist Dysregulation Profile), and examined whether parental mentalization (operationalized as Parental Reflective Functioning and Mind-Mindedness, assessed using Diamond Maternal Reflective Functioning Scale and interactional 20-min play sessions, respectively) mediated this relationship, in a clinical sample of 90 mother-child dyads (child M age = 19.

The role of social media messages and content creators in shaping COVID-19 vaccination intentions.

Introduction: Social media plays a crucial role in shaping health behaviors by influencing users' perceptions and engagement with health-related content. Understanding these dynamics is important as new social media technologies and changing health behaviors shape how people engage with health messages.

Aim: The current study explored the relationship between the characteristics of content creators, the messaging strategies employed in social media, and users' engagement with social media content, and whether these features are linked to users' behavioral intentions.

Optimizing parenting and child outcomes following parent-child interaction therapy - toddler: a randomized controlled trial.

Background: Parent-Child Interaction Therapy-Toddler (PCIT-T) is an attachment-informed intervention model designed to meet the specific developmental needs of toddlers aged 12-24 months presenting with challenging behaviors.

Methods: This study used a randomized controlled design to evaluate outcomes of PCIT-T for children aged 14-24 months with disruptive behaviors. Ninety toddlers with parent-reported disruptive behavior were randomly allocated to PCIT-T (intervention), an active control condition (Circle of Security- Parenting™; COS-P), or a non-treatment control condition (wait-list; WL).

Real-world outcomes for high-risk non-muscle-invasive bladder cancer: screened patients for the BRAVO trial.

Objective: To report real-world outcomes for high-risk non-muscle-invasive bladder cancer (HRNMIBC), including bacillus Calmette-Guérin (BCG) and radical cystectomy (RC), as randomised comparisons of these have not been possible.

Methods: We detail consecutive participants screened for the BRAVO randomised controlled trial comparing RC with BCG (International Standard Randomised Controlled Trial Number [ISRCTN]12509361). Patients were prospectively registered and case-note review used for outcomes.

Australians with chronic lymphocytic leukaemia continue to have high rates of second primary malignancies in the modern era.

Population-based studies have demonstrated a high risk of second cancers, especially of the skin, among patients with chronic lymphocytic leukaemia (CLL). We describe age-standardised incidence ratios (SIRs) of second primary malignancies (SPM) in Australian patients with relapsed/refractory CLL treated with at least two lines of therapy, including ibrutinib. From December 2014 to November 2017, 156 patients were identified from 13 sites enrolled in the Australasian Lymphoma and Related Diseases Registry, and 111 had follow-up data on rates of SPM.

The Effects of Animations and Multimedia Messages on Public Engagement in Precision Medicine: Assessment of Moderation and Mediation.

Public participation in precision medicine (PM) research is essential to achieving effective health care but has been impeded by a lack of awareness and basic knowledge. There is a critical need for educational materials that can clearly explain PM to foster involvement. This randomized controlled trial with a posttest-only control group design aims to assess the effects of educational messages delivered through animations relative to live-action videos and leaflets on intentions of involvement in PM research.

The role of perceived expertise and trustworthiness in research study and clinical trial recruitment: Perspectives of clinical research coordinators and African American and Black Caribbean patients.

This study investigates the role of source credibility on minority participant recruitment, particularly African American and Black Caribbean patients. A total of nine focus groups (N = 48 participants) were conducted with both patient groups and clinical research coordinators (CRCs). Using the elaboration likelihood model as a guiding framework for analysis, this study found that the credibility of research coordinators (or other professionals who recruit for research studies and clinical trials) was instrumental in shaping attitudes of prospective participants.

Reducing Health Disparities Among African American and Black Caribbean Patients by Improving the Communication Practices of Clinical Research Coordinators.

This manuscript focuses on the communication factors that affect the willingness of African Americans and Black Caribbean patients to participate in clinical trials and research studies. Low rates of research participation by members of communities of color have long been linked to health disparities. While there are many factors that contribute to low rates of accrual of African American and Black patients to clinical trials, a lack of attention to communication factors that enhance or inhibit the recruitment process is central to the problem.

Assessing the role of interactivity: An evaluation of information aids to support the enrollment of precision medicine research programs.

Objective: Recruiting diverse participants for precision medicine (PM) research programs should overcome low literacy and varied expectations. Information aids (IA) can address these barriers through patient-centered education. The purpose of this study was to evaluate the effectiveness of three information aids (IA) on participating in PM.

Measuring the processes of interdisciplinary team collaboration: Creating valid measures using a many-facet Rasch model approach.

Introduction: The science of team science (SciTS) is an emerging research area that studies the processes and outcomes of team-based research. A well-established conceptual framework and appropriate methodology for examining the effectiveness of team science are critically important for promoting and advancing collaborative and interdisciplinary research. Although many instruments have been developed and used in the SciTS field, psychometric evidence has not been routinely assessed or reported for these scales.

Clinical characteristics of Australian treatment-naïve patients with classical Hodgkin lymphoma from the lymphoma and related diseases registry.

Comprehensive clinical characteristics of Australian patients with classical Hodgkin Lymphoma (cHL) have not previously been systematically collected and described. We report real-world data of 498 eligible patients from the first 5 years of the Lymphoma and Related Diseases Registry (LaRDR), including baseline characteristics, histologic subtype, and treatment patterns in first-line therapy. Patient demographics and distribution of histopathological subtypes of cHL are similar to reported international cohorts.

Integration of a Nationally Recognized Tobacco Treatment Specialist Certification into Health Sciences Curricula: A short report.

Tobacco use impacts every organ in the body. Dental professionals observe the detrimental oral and systemic consequences of tobacco use. Routine dental hygiene and dental appointments are an ideal opportunity for tobacco cessation discussions.

Lessons learned from the "Goodie Box": A message design study developed and evaluated in community settings for cervical cancer prevention.

Despite the availability of free pap testing services, Jamaican women have low human papillomavirus (HPV) screening rates; 16% of women in the Kingston Metropolitan Area have been screened within the prior 3 years. This paper discusses the testing of theory-based messages to increase HPV screening uptake in a low-resource setting, using HPV self-test kits designed for this intervention. A total of 163 Jamaican women, aged 30-65 years, who had not had a pap test in at least 3 years, from two low socioeconomic status communities in Kingston, were enrolled and assigned to one of two versions of an HPV self-test kit, either with or without culturally targeted fear appeal messages.

Impact of Tumour Epstein-Barr Virus Status on Clinical Outcome in Patients with Classical Hodgkin Lymphoma (cHL): A Review of the Literature and Analysis of a Clinical Trial Cohort of Children with cHL.

In this study, we have re-evaluated how EBV status influences clinical outcome. To accomplish this, we performed a literature review of all studies that have reported the effect of EBV status on patient outcome and also explored the effect of EBV positivity on outcome in a clinical trial of children with cHL from the UK. Our literature review revealed that almost all studies of older adults/elderly patients have reported an adverse effect of an EBV-positive status on outcome.

NeuroSAFE PROOF: study protocol for a single-blinded, IDEAL stage 3, multi-centre, randomised controlled trial of NeuroSAFE robotic-assisted radical prostatectomy versus standard robotic-assisted radical prostatectomy in men with localized prostate cancer.

Background: Robotic radical prostatectomy (RARP) is a first-line curative treatment option for localized prostate cancer. Postoperative erectile dysfunction and urinary incontinence are common associated adverse side effects that can negatively impact patients' quality of life. Preserving the lateral neurovascular bundles (NS) during RARP improves functional outcomes.

Evaluation of a Tobacco Treatment Training Program.

There is a need for program evaluations associated with educating healthcare professionals about the treatment of patients who use tobacco. The purpose of this study was to evaluate a Tobacco Treatment Specialist Training program with a pre-test and post-test (provided six months after the program) to determine if participants-maintained knowledge and practices to help patients with tobacco cessation in a mixed-model analysis. A pre-test survey was administered to attendees of a three-day tobacco treatment training continuing education certification program.

A pilot clinical study to Evaluate Liraglutide-mediated Anti-platelet activity in patients with type-2 Diabetes (ELAID study).

Background: Liraglutide is an effective treatment for the management of type 2 diabetes mellitus (T2DM). In addition to glycemic control and potential cardioprotective effects, recent studies suggest a possible role for liraglutide in the inhibition of platelet reactivity, further attenuating atherothrombotic risk in patients with T2DM. We evaluated the in-vivo antiplatelet effect of liraglutide in T2DM patients without macrovascular disease or concurrent anti-platelet therapy.

Centre-based comparison of double versus single prevention strategy on transfusion-transmitted cytomegalovirus in at-risk haemopoietic stem cell transplant patients and a state survey on cytomegalovirus-seronegative ordering practises.

Background: Universal leucocyte depletion reduces the risk of transfusion-transmitted cytomegalovirus; however, many clinicians still prescribe cytomegalovirus seronegative units.

Aim: Our retrospective study aims to confirm the low risk of transfusion-transmitted cytomegalovirus with leucocyte depletion alone and demonstrate the ongoing variability in cytomegalovirus seronegative transfusion prescribing.

Methods: Over a 9-year period (July 2009-July 2018), occurrences of transfusion transmitted cytomegalovirus in cytomegalovirus seronegative donor/recipient haemopoietic stem cell transplant pairs were compared at one allogeneic haemopoietic stem cell transplant centre providing cytomegalovirus seronegative blood products and leucocyte depletion (double prevention) versus another providing leucocyte depletion only (single prevention).