Publications by authors named "Sungkwon Cho"

Article Synopsis
  • * Current tobacco users showed a significantly higher risk of poor HRQoL compared to those who have never smoked, particularly in areas like mobility and pain/discomfort.
  • * The findings suggest that both combustible cigarettes and non-combustible nicotine products negatively impact HRQoL, highlighting the need for improved smoking cessation strategies and lifestyle changes to support users.
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Article Synopsis
  • A nationwide study in Korea examined the link between tobacco use and generalized anxiety disorder (GAD) using data from over 5,400 adults.
  • The findings indicated that both combustible cigarette smokers and users of noncombustible nicotine products (NNTPs) had significantly higher odds of experiencing GAD compared to those who have never used tobacco.
  • Former tobacco users showed no significant association with GAD compared to never users, highlighting the importance of screening and early intervention for anxiety among current tobacco users.
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Hypoxia is an important cause of acute kidney injury (AKI) in various conditions because kidneys are one of the most susceptible organs to hypoxia. In this study, we investigated whether nicotinamide adenine dinucleotide 3-phosphate (NADPH) oxidase 4 (Nox4) plays a role in hypoxia induced AKI in a cellular and animal model. Expression of Nox4 in cultured human renal proximal tubular epithelial cells (HK-2) was significantly increased by hypoxic stimulation.

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Background: Colistin (polymyxin E) is an important constituent of the polymyxin class of cationic polypeptide antibiotics. Intrarenal oxidative stress can contribute to colistin-induced nephrotoxicity. Nicotinamide adenine dinucleotide 3-phosphate oxidases (Noxs) are important sources of reactive oxygen species.

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Contrast-induced acute kidney injury (CIAKI) is a leading cause of acute kidney injury following radiographic procedures. Intrarenal oxidative stress plays a critical role in CIAKI. Nicotinamide adenine dinucleotide 3-phosphate (NADPH) oxidases (Noxs) are important sources of reactive oxygen species (ROS).

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