Publications by authors named "Sudharshan Tripathi"

Background: The pelvic ring plays a pivotal role in maintaining biomechanical stability during upright posture. While lumbopelvic fixation is effective for stabilizing unstable pelvic fractures, the influence of spinopelvic alignment, particularly sacral slope on fixation mechanics and stress on adjacent joints, has not been adequately investigated.

Methods: A finite element model of the lumbar spine, pelvis, and femur was used to simulate a pelvic ring fracture.

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Background: Low back pain affects over 80 % of adults, with sacroiliac joint dysfunction accounting for 15-30 % of these cases. Sacroiliac fusion is a surgical procedure for refractory joint pain. While the biomechanics of the joint and its fusion relative to the spinal column are well-known, the hip-spine relationship post-fusion remains unclear.

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Article Synopsis
  • - The study focuses on the biomechanical stabilization of the occipitocervical junction using novel multi-rod constructs to address challenging pathologies that arise due to limited bone surfaces in this area.
  • - Researchers evaluated different rod configurations (2-rod TI, 2-rod CoCr, 3-rods, and 4-rods) and used finite element modeling to assess stress and range of motion across the OC-C4 junction.
  • - Results indicated that 3- and 4-rod constructs exhibit lower stress on the rods compared to 2-rod constructs, while showing similar functionality regarding range of motion and discal stresses.
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Purpose: To assess the effect of various pelvic fixation techniques and number of rods on biomechanics of the proximal junction of long thoracolumbar posterior instrumented fusions.

Methods: A validated spinopelvic finite-element (FE) model was instrumented with L5-S1 ALIF and one of the following 9 posterior instrumentation configurations: (A) one traditional iliac screw bilaterally ("2 Iliac/2 Rods"); (B) T10 to S1 ("Sacral Only"); (C) unilateral traditional iliac screw ("1 Iliac/2 Rods"); (D) one traditional iliac screw bilaterally with one midline accessory rod ("2 Iliac/3 rods"); (E) S2AI screws connected directly to the midline rods ("2 S2AI/2 Rods"); and two traditional iliac screws bilaterally with two lateral accessory rods connected to the main rods at varying locations (F1: T10-11, F2: T11-12, F3: T12-L1, F4: L1-2) ("4 Iliac/4 Rods"). Range of motions (ROM) at T10-S1 and T9-T10 were recorded and compared between models.

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Background: Pedicle subtraction osteotomy (PSO) is effective for correcting spinal malalignment but is associated with high complication rates. The biomechanical effect of different PSO levels remains unclear, and no finite element (FE) analysis has compared L2-, L3-, L4-, and L5-PSOs.

Purpose: To assess the effects of PSO level on the spine's global range of motion, stresses on posterior instrumentation, load sharing with the anterior column, and proximal junctional stresses.

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Article Synopsis
  • Slipped capital femoral epiphysis (SCFE) is a common hip disorder in children, and recent research indicates that the alignment of the spine could impact the slippage of the femoral growth plate.
  • This study employed finite element analysis using CT scans to simulate different spinal alignments and their effects on shear stress during various physical activities.
  • Results showed that posterior pelvic tilt is associated with higher shear stress on the growth plate, especially during activities like walking and one-leg stance, which may increase the risk of SCFE in individuals with this alignment.
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Article Synopsis
  • Pelvic ring fractures are increasingly common in older adults, with high mortality rates of 10% to 16%, necessitating effective stabilization methods through internal fixation due to the complexity of these injuries.!* -
  • A study used a 3D finite element model to simulate a unilateral pelvic ring fracture and tested five fixation techniques, measuring their biomechanical performance, including range of motion and stress levels at various locations.!* -
  • Results showed that trans-iliac-trans-sacral screw fixation provided the best stabilization against displacement, while different fixation techniques varied in effectiveness for stabilizing specific fracture sites and managing range of motion in the lumbar spine and pelvis.!*
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Objective: To determine the effects of thoracic stiffness on mechanical stress in the lumbar spine during motion.

Methods: To evaluate the effect of preoperative thoracic flexibility, stiff and flexible spine models were created by changing the material properties of ligaments and discs in the thoracic spine. Total laminectomy was performed at L4/5 in stiff and flexible models.

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Purpose: To develop and validate a finite element (FE) model of a sacral pedicle subtraction osteotomy (S1-PSO) and to compare biomechanical properties of various multi-rod configurations to stabilize S1-PSOs.

Methods: A previously validated FE spinopelvic model was used to develop a 30° PSO at the sacrum. Five multi-rod techniques spanning the S1-PSO were made using 4 iliac screws and a variety of primary rods (PR) and accessory rods (AR; lateral: Lat-AR or medial: Med-AR).

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Objective: Lumbar spinal canal stenosis (LSS) with diffuse idiopathic skeletal hyperostosis (DISH) can require revision surgery because of the intervertebral instability after decompression. However, there is a lack of mechanical analyses for decompression procedures for LSS with DISH.

Methods: This study used a validated, three-dimensional finite element model of an L1-L5 lumbar spine, L1-L4 DISH, pelvis, and femurs to compare the biomechanical parameters (range of motion [ROM], intervertebral disc, hip joint, and instrumentation stresses) with an L5-sacrum (L5-S) and L4-S posterior lumbar interbody fusion (PLIF).

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Objective: Spinopelvic parameters are vital components that must be considered when treating patients with spinal disease. Several finite element (FE) studies have explored spinopelvic parameters such as sacral slope (SS) and the impact on the lumbar spine, although no study has examined the effect on the hip and sacroiliac joint (SIJ) on varying SS angles. Therefore, it is necessary to have a biomechanical understanding of the impact on the spinopelvic complex.

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Objective: This finite element analysis aimed to investigate the effects of surgical procedures for cervical spine injury.

Methods: A three-dimensional finite element model of the cervical spine (C2-C7) was created from computed tomography. This model contained vertebrae, intervertebral discs, anterior longitudinal ligament, and posterior ligament complex.

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Introduction: The correlation between cervical alignment and clinical outcome of total disc replacement (TDR) surgery is arguable. We believe that this conflict exists because the parameters that influence the biomechanics of the cervical spine are not well understood, specifically the effect of TDR on different cervical alignments.

Methods: A validated osseo-ligamentous model from C2-C7 was used in this study.

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Purpose: Anterior and posterior decompressions for cervical myelopathy and radiculopathy may lead to clinical improvements. However, patients with kyphotic cervical alignment have sometimes shown poor clinical outcomes with posterior decompression. There is a lack on report of mechanical analysis of the decompression procedures for kyphotic cervical alignment.

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Objective: Soft tissue cervical spine injury (CSI) has the possibility of causing cervical segmental instability, which can lead to spinal cord injury. There is a lack of certainty in assessing whether soft tissue CSI is unstable or not. This biomechanical study aimed to investigate the risk factors of soft tissue CSI.

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