Curved Anthracenes for Visible-Light Photon Energy Storage Dewar Isomerization.

We report the design of curved anthracene systems that undergo efficient Dewar isomerization upon visible light absorption and release heat through thermally triggered reverse isomerization, with high cyclability. These systems achieve remarkably high energy storage capacities-up to 170 kJ/mol and 0.65 MJ/kg-comparable to the best reported MOST materials, while offering the added capability of harnessing standard solar spectrum and presenting chemical robustness.

Self-Activated Energy Release Cascade from Anthracene-Based Solid-State Molecular Solar Thermal Energy Storage Systems.

We introduce donor-acceptor substituted anthracenes as effective molecular solar thermal energy storage compounds that operate exclusively in the solid state. The donor-acceptor anthracenes undergo visible light-induced [4+4] cycloaddition reaction, producing metastable cycloadducts, dianthracenes with quaternary carbons, and storing photon energy. The triggered cycloreversion of dianthracenes to anthracenes discharges the stored energy as heat in the order of 100 kJ/mol (200 J/g).

Differential colitis susceptibility of Th1- and Th2-biased mice: A multi-omics approach.

The health and economic burden of colitis is increasing globally. Understanding the role of host genetics and metagenomics is essential to establish the molecular basis of colitis pathogenesis. In the present study, we have used a common composite dose of DSS to compare the differential disease severity response in C57BL/6 (Th1 biased) and BALB/c (Th2 biased) mice with zero mortality rates.

Paracetamol and other acetanilide analogs as inter-molecular hydrogen bonding assisted diamagnetic CEST MRI contrast agents.

Paracetamol and a few other acetanilide derivatives are reported as a special class of diamagnetic Chemical Exchange Saturation Transfer (diaCEST) MRI contrast agents, that exhibit contrast only when the molecules form inter-molecular hydrogen bonding mediated molecular chains or sheets. Without the protection of the hydrogen bonding their contrast producing labile proton exchanges too quickly with the solvent to produce any appreciable contrast. Through a number of variable temperature experiments we demonstrate that under the conditions when the hydrogen bond network breaks and the high exchange returns back, the contrast drops quickly.

(Z)-Selective anti-Markovnikov or Markovnikov thiol-yne-click reactions of an internal alkyne by amide hydrogen bond control.

Herein, we show exclusive control of stereo and regioselective thiol-yne click (TYC) reactions of internal alkynes via amide hydrogen bond control. By exploiting appropriate hydrogen bonding interactions like N-HS, N-HN and C-HO, either (Z)-selective anti-Markovnikov or Markovnikov products could be obtained for an internal alkyne, exclusively.

GG reverses mortality of neonatal mice against challenge.

Pathogenic infection is one of the major causes of death in newborns. Antibiotic based therapies are still the major mode of treatment for infection. Increased usage of antibiotics leads to selective evolution of microorganisms and causes diseases in adulthood.

Seven coordinate Co(ii) and six coordinate Ni(ii) complexes of an aromatic macrocyclic triamide ligand as paraCEST agents for MRI.

We are reporting Co(ii) and Ni(ii) complexes of a pyridine containing aromatic macrocyclic triamide ligand, 3,6,9,15-tetraazabicyclo(9.3.1)pentadeca-1(15),11,13-triene-3,6,9-triacetamide (TPTA), as paramagnetic chemical exchange saturation transfer (paraCEST) MRI contrast agents.

Spin-lattice relaxation studies on deep eutectic solvent/Choliniumtetrachloroferrate mixtures: Suitability of DES-based systems towards magnetic resonance imaging studies.

This study has been undertaken with an aim to investigate the suitability of the deep eutectic solvents (DES)-based systems for magnetic resonance imaging studies. DESs are used to develop the systems, keeping in mind the fact that these are relatively less toxic than ionic liquids, and hence, DES based magnetic compound is expected to be relatively less toxic than magnetic ionic liquids. In this work, spin-lattice (T ) relaxation measurements are carried out in the binary mixtures of deep eutectic solvent with a paramagnetic component choliniumtetrachloroferrate ([Ch][FeCl ]).