Exploring the anti-diabetic potential of : isolation and characterization of bioactive compounds.

We investigated the anti-diabetic effects of the ethyl acetate fraction of and its isolated compounds using both and study models. tests showed that the ethyl acetate part of and its separate compounds had better activity blocking α-glucosidase, α-amylase, and α-lipase. The ethyl acetate fraction and its active constituents, barbaloin and gallic acid, significantly ( < 0.

A Selective Review on the Novel Approaches and Potential Control Agents of Anti-biofouling and Anti-biofilming.

Specific aggregates of bacterial colonies, which, when embedded in a self-produced matrix, are known to cause biofouling. These complex structures are highly resistant to extreme stress conditions like antibiotics, complex cleaning strategies, or even the human immune system. The formation of biofilm matrices and biofouling is chosen as the preferred microbial environment owing to the advantages offered for the embedded cells for their long-term survival.

Approaches towards the enhanced production of Rapamycin by Streptomyces hygroscopicus MTCC 4003 through mutagenesis and optimization of process parameters by Taguchi orthogonal array methodology.

The present research was conducted to define the approaches for enhanced production of rapamycin (Rap) by Streptomyces hygroscopicus microbial type culture collection (MTCC) 4003. Both physical mutagenesis by ultraviolet ray (UV) and chemical mutagenesis by N-methyl-N-nitro-N-nitrosoguanidine (NTG) have been applied successfully for the improvement of Rap production. Enhancing Rap yield by novel sequential UV mutagenesis technique followed by fermentation gives a significant difference in getting economically scalable amount of this industrially important macrolide compound.

Kinetics of rapamycin production by Streptomyces hygroscopicus MTCC 4003.

Research work was carried out to describe the kinetics of cell growth, substrate consumption and product formation in batch fermentation of rapamycin using shake flask as well as laboratory-scale fermentor. Fructose was used as the sole carbon source in the fermentation media. Optimization of fermentation parameters and reliable mathematical models were used for the maximum production of rapamycin from Streptomyces hygroscopicus MTCC 4003.

Decolorization and biodegradation of congo red dye by a novel white rot fungus Alternaria alternata CMERI F6.

A novel white rot fungus Alternaria alternata CMERI F6 decolorized 99.99% of 600 mg/L congo red within 48 h in yeast extract-glucose medium at 25 °C, pH 5 and 150 rpm. Physicochemical parameters like carbon and nitrogen sources, temperature, pH and aeration were optimized to develop faster decolorization process.

Kinetics of phenol biodegradation at high concentration by a metabolically versatile isolated yeast Candida tropicalis PHB5.

A highly tolerant phenol-degrading yeast strain PHB5 was isolated from wastewater effluent of a coke oven plant and identified as Candida tropicalis based on phylogenetic analysis. Biodegradation experiments with C. tropicalis PHB5 showed that the strain was able to utilize 99.