Publications by authors named "Stephane Genevay"

Purpose: Near-Peer Training (NPT) is increasingly used to teach clinical and procedural skills during undergraduate medical education. The impact of NPT programs on clinical practice is usually measured through OSCE stations that assess the trained skills. Little is known about the impact of a single NPT session on students' performance in OSCEs.

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The International Association for the Study of Pain currently recognizes three types of pain : nociceptive, neuropathic, and nociplastic. This article summarizes the current consensus, allowing clinicians to categorize patients with low back pain according to the predominant mechanisms, and suggests ways to provide personalized care.

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Despite the frequency and societal impact of common low back pain, its exact pathophysiology remains poorly understood and the subject of much debate. A review of the literature shows the coexistence of three main models, none of which seems to withstand detailed analysis of the currently available data. This article describes the basis of an emerging model called "dysfunctional" (or "non-lesional" in the Anglo-Saxon literature), which considers spinal neuromuscular dysfunction as the main biological basis to be integrated into the biopsychosocial paradigm.

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Objective: To address the comparative effectiveness of common interventional procedures for chronic non-cancer (axial or radicular) spine pain.

Design: Systematic review and network meta-analysis (NMA) of randomised controlled trials (RCTs).

Data Sources: Medline, Embase, CINAHL, CENTRAL, and Web of Science from inception to 24 January 2023.

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Article Synopsis
  • The clinical question investigates the effectiveness and safety of common interventional procedures for chronic spine pain not related to cancer or inflammatory diseases.
  • Current practice highlights the prevalence of chronic spine pain and the inconsistent recommendations given to patients seeking treatment options.
  • The guideline panel strongly advises against several interventional procedures for both chronic axial and radicular spine pain, underscoring the importance of evidence-based practices when managing this condition.
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Tumor-induced osteomalacia (TIO) is a rare acquired paraneoplastic syndrome caused by a mesenchymal tumor secreting a phosphaturic hormone called FGF23. Patients present with bone pain, fragility fractures and muscle weakness. Biochemical results show hypophosphatemia, raised serum alkaline phosphatase and reduced calcitriol.

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The flexion relaxation phenomenon (FRP) is characterized by the reduction of paraspinal muscle activity at maximum trunk flexion. FRP is reported to be altered (persistence of spinal muscle activity) in more than half of nonspecific chronic low back pain (NSCLBP) patients. Little is known about how the multi-segmental spine affects FRP.

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The flexion-relaxation phenomenon (FRP) is frequently absent among non-specific chronic low back pain (NSCLBP) patients. However, it is unknown whether this absence is intrinsic to their pathology or merely a consequence of reduced trunk flexion. Immersive virtual reality (IVR) can create a patient avatar whose range of motion can be modulated to differ from the real movement.

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For several decades now, chronic spinal pain has been one of the most prevalent health problems in virtually every country in the world. Although most scientific research has focused on the intervertebral disc, this has unfortunately not yet led to truly effective treatments. Fortunately, other groups have resolutely tackled this challenge by adopting a complexity-based perspective, paving the way for the emergence of promising new therapeutic approaches.

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Article Synopsis
  • - This year in rheumatology has seen advancements in understanding rheumatoid arthritis and low back pain mechanisms, improving diagnosis and management strategies.
  • - Key studies were released on gout, axial spondyloarthritis, autoinflammatory diseases, and systemic vasculitides, along with updated treatment guidelines from ASAS-EULAR and EULAR/PReS.
  • - New safety data on JAK inhibitors emerged, as well as innovative glucocorticoid-sparing strategies for treating giant cell arteritis.
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Introduction: The clinical course of LBP is complex and chronicity is more frequent than once thought. Moreover, insufficient evidence was found in support of any specific approach at the level of the general population.

Research Question: This study aimed to evaluate the effectiveness of providing a back care package through the primary healthcare system in decreasing the rate of CLBP in the community.

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At last, chronic pain, with its consequences and impact for patients and society, is now considered as a disease in its own in the 11th revision of the international classification of diseases (ICD). We present here in the light of two clinical cases, why the diagnosis of chronic primary pain is useful and how to utilize these new codes. We hope to rapidly see the awaited impact on the healthcare system (from the patient care to insurance issues), as on research and teaching.

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Article Synopsis
  • The study aims to identify reliable and valid movement biomarkers that can differentiate patients with non-specific chronic low back pain (NSCLBP) from asymptomatic individuals, which may improve patient follow-up and treatment strategies.
  • It assessed 72 movement biomarkers on 30 asymptomatic participants and 30 NSCLBP patients, examining their reliability, validity, and interpretability.
  • Four key biomarkers (maximal lumbar sagittal angle, lumbar sagittal angle range of motion, mean lumbar sagittal angular velocity, and maximal upper lumbar sagittal angle) were found to reliably and validly distinguish NSCLBP patients from asymptomatic individuals, indicating a potential for enhancing diagnosis and treatment approaches.
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Background: Among the main methods used to identify an altered flexion relaxation phenomenon (FRP) in nonspecific chronic low back pain (NSCLBP), it has been previously demonstrated that flexion relaxation ratio (FRR) and extension relaxation ratio (ERR) are more objective than the visual reference method.

Objective: To determine the sensitivity and specificity of the different methods used to calculate the ratios in terms of their ability to identify an altered FRP in NSCLBP.

Methods: Forty-four NSCLBP patients performed a standing maximal trunk flexion task.

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The so-called 4P medicine, preventive, predictive, participatory, and personalized, which places the patient at the center has influenced the latest recommendations for the management of common low back pain. The management of low back pain in the acute, subacute, and chronic phase is currently based on the profile of each patient with their risk factors, their prognosis, and the respect of their preferences, promoting an integrative approach. During the first consultation, it is important to identify factors of moderate to poor prognosis, including kinesiophobia and to search for false beliefs, through a detailed medical history.

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Healthcare workers have potentially been among the most exposed to SARS-CoV-2 infection as well as the deleterious toll of the pandemic. This study has the objective to differentiate the pandemic toll from post-acute sequelae of SARS-CoV-2 infection in healthcare workers compared to the general population. The study was conducted between April and July 2021 at the Geneva University Hospitals, Switzerland.

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Background: Persistent symptoms of SARS-CoV-2 are prevalent weeks to months following the infection. To date, it is difficult to disentangle the direct from the indirect effects of SARS-CoV-2, including lockdown, social, and economic factors.

Objective: The study aims to characterize the prevalence of symptoms, functional capacity, and quality of life at 12 months in outpatient symptomatic individuals tested positive for SARS-CoV-2 compared to individuals tested negative.

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Low back pain is a major public health problem, with a significant physical and psychosocial impact. Inappropriate use of diagnostic imaging is one of the main factors contributing to the costs of these conditions. In addition, there is evidence to suggest that imaging and the accompanying report are risk factors for chronicity.

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Background And Objectives: Low back pain (LBP) is a common health condition in populations. Limited large-scale population-based studies evaluated the prevalence and predictors of LBP in developing countries. This study aimed to evaluate the prevalence and factors associated with LBP among the Iranian population.

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In rheumatology, this year has seen an expansion of knowledge about the effects of COVID and the vaccine response in patients with autoimmune diseases, but also a re-examination of the usual doses of glucocorticoids in vasculitides and new treatments strategies for diseases such as systemic lupus erythematosus, spondylarthritis and rheumatoid arthritis. New criteria for imaging assessment in spondylarthritis and new management guidelines for patients with low back pain have also been proposed.

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