Navigating life's challenges: A randomized 6-week online intervention study to enhance resilience in working-age adults.

Psychological resilience describes a trainable capacity that allows us to cope with adversity and adapt to stressful life events. This study aimed to investigate the efficacy of a 6-week online resilience intervention in students and working-age individuals. We randomly assigned 174 participants aged between 18 and 54 years (74.

Effects of rhythmic-cued gait training on gait-like task related brain activation in people with multiple sclerosis.

Background: Walking impairment is one of the most debilitating symptoms of multiple sclerosis (MS). A better understanding of brain mechanisms underlying successful gait training could help to improve development of targeted therapy. We therefore investigated changes in brain activation associated with improvements in walking function after rhythmic-cued gait training.

Actual and Imagined Music-Cued Gait Training in People with Multiple Sclerosis: A Double-Blind Randomized Parallel Multicenter Trial.

Background: Actual and imagined cued gait trainings have not been compared in people with multiple sclerosis (MS).

Objective: To analyze the effects of cued motor imagery (CMI), cued gait training (CGT), and combined CMI and cued gait training (CMI-CGT) on motor, cognitive, and emotional functioning, and health-related quality of life in people with MS.

Methods: In this double-blind randomized parallel-group multicenter trial, people with MS were randomized (1:1:1) to CMI, CMI-CGT, or CGT for 30 minutes, 4×/week for 4 weeks.

Evaluation of the T25FW in minimally disabled people with multiple sclerosis.

Background: Walking impairment is one of the most prevalent symptoms in people with multiple sclerosis (pwMS). In this study, we aimed to explore the usefulness of a simple walking test, the Timed 25 Foot Walk (T25FW), in detecting subtle differences in "fully ambulatory" pwMS compared to HC.

Methods: We therefore investigated retrospective data from a clinical real-life cohort of 650 pwMS.

Evaluation of a self-administered iPad-based processing speed assessment for people with multiple sclerosis in a clinical routine setting.

Background: Limited resources often hinder regular cognitive assessment of people with multiple sclerosis (pwMS) in standard clinical care. A self-administered iPad®-based cognitive screening-tool (Processing Speed Test; PST) might mitigate this problem.

Objective: To evaluate the PST in clinical routine.

Psychological factors and brain magnetic resonance imaging metrics associated with fatigue in persons with multiple sclerosis.

Background: Besides demographics and clinical factors, psychological variables and brain-tissue changes have been associated with fatigue in persons with multiple sclerosis (pwMS). Identifying predictors of fatigue could help to improve therapeutic approaches for pwMS. Therefore, we investigated predictors of fatigue using a multifactorial approach.

Information processing speed as a prognostic marker of physical impairment and progression in patients with multiple sclerosis.

Background: Prediction of disability progression in patients with MS (pwMS) is challenging. So far, scarce evidence exists suggesting knowledge about how cognitive performance may potentially improve prediction of physical impairment and disability progression in MS. Therefore, we wanted to assess the prognostic value of cognitive performance regarding physical impairment and disability progression in pwMS.