Publications by authors named "Sophie A Kupiec-Weglinski"

Article Synopsis
  • In 2019, new guidelines were created to help understand a condition called chronic limb-threatening ischemia (CLTI) and a concept called limb-based patency (LBP), which means keeping blood flow in a targeted artery after treatment.
  • The study looked at patients from 2016 to 2019 who had surgery for CLTI, focusing on whether keeping LBP was connected to serious problems like amputations or surgeries after treatment.
  • Out of 184 limbs studied, many patients had diabetes and severe tissue loss; results showed that losing LBP was a strong predictor of future serious limb problems.
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Pancreas transplantation in patients with type 2 diabetes (T2D) remains relatively uncommon compared with pancreas transplantation in patients with type 1 diabetes (T1D); however, several studies have suggested similar outcomes between T2D and T1D, and the practice has become increasingly common. Despite this growing interest in pancreas transplantation in T2D, no study has systematically summarized the data to date. We systematically reviewed the literature on pancreas transplantation in T2D patients including patient and graft survival, glycemic control outcomes, and comparisons with outcomes in T2D kidney transplant alone and T1D pancreas transplant recipients.

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Article Synopsis
  • This study evaluates the accuracy of a mortality prediction model for patients undergoing revascularization due to chronic limb-threatening ischemia (CLTI), comparing expected outcomes with those observed in a specific medical center.
  • Analyzing 195 procedures on 169 patients, the research found significant differences in comorbidities and patient demographics compared to the Vascular Quality Initiative (VQI) database, including higher rates of unstable angina and dialysis dependence.
  • While the observed 30-day mortality rates were higher than the VQI estimates across all risk groups, the study concluded that the VQI model still effectively stratified patients based on mortality risk.
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