Publications by authors named "Sophia Shen"

Article Synopsis
  • Scientists studied B cells in pancreatic cancer patients to see how they affect health and found that certain antigens help B cells respond better.* -
  • They used advanced technology to analyze immune cells from tumors and discovered three important proteins that B cells recognize.* -
  • Higher levels of antibodies against two of these proteins were found in cancer patients, suggesting that the body's immune system might be reacting to its own cells in a disease state.*
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Since its outbreak in 2019, COVID-19 becomes a pandemic, severely burdening the public healthcare systems and causing an economic burden. Thus, societies around the world are prioritizing a return to normal. However, fighting the recession could rekindle the pandemic owing to the lightning-fast transmission rate of SARS-CoV-2.

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Electronic textiles are fundamentally changing the way we live. However, the inability to effectively recycle them is a considerable burden to the environment. In this study, we developed a cotton fiber-based piezoresistive textile (CF p-textile) for biomonitoring which is biocompatible, biodegradable, and environmentally friendly.

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The hands are used in all facets of daily life, from simple tasks such as grasping and holding to complex tasks such as communication and using technology. Finding a way to not only monitor hand movements and gestures but also to integrate that data with technology is thus a worthwhile task. Gesture recognition is particularly important for those who rely on sign language to communicate, but the limitations of current vision-based and sensor-based methods, including lack of portability, bulkiness, low sensitivity, highly expensive, and need for external power sources, among many others, make them impractical for daily use.

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Continuously and accurately monitoring pulse-wave signals is critical to prevent and diagnose cardiovascular diseases. However, existing wearable pulse sensors are vulnerable to motion artifacts due to the lack of proper adhesion and conformal interface with human skin during body movement. Here, a highly sensitive and conformal pressure sensor inspired by the kirigami structure is developed to measure the human pulse wave on different body artery sites under various prestressing pressure conditions and even with body movement.

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Cardiovascular diseases remain the leading cause of death worldwide. The rapid development of flexible sensing technologies and wearable pressure sensors have attracted keen research interest and have been widely used for long-term and real-time cardiovascular status monitoring. Owing to compelling characteristics, including light weight, wearing comfort, and high sensitivity to pulse pressures, physiological pulse waveforms can be precisely and continuously monitored by flexible pressure sensors for wearable health monitoring.

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Electronic textiles (e-textiles), having the capability of interacting with the human body and surroundings, are changing our everyday life in fundamental and meaningful ways. Yet, the expansion of the field of e-textiles is still limited by the lack of stable and biocompatible power sources with aesthetic designs. Here, we report a rechargeable solid-state Zn/MnO fiber battery with stable cyclic performance exceeding 500 hours while maintaining 98.

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In this study, we present the observation of the giant magnetoelastic effect that occurs in soft elastomer systems without the need of external magnetic fields and possesses a magnetomechanical coupling factor that is four times larger than that of traditional rigid metal-based ferromagnetic materials. To investigate the fundamental scientific principles at play, we built a linear model by using COMSOL Multiphysics, which was consistent with the experimental observations. Next, by combining the giant magnetoelastic effect with electromagnetic induction, we developed a magnetoelastic generator (MEG) for biomechanical energy conversion.

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Water pollution is one of the leading causes of death and disease worldwide, yet mitigating it remains a challenge. This paper presents an efficient new strategy for the processing of wastewater utilizing an accessible redox reaction with MoSe nanoflowers, which shows a strong oxidizing ability and permits the decomposition of dye molecules in dark environments without the need for an external power source. This reaction can treat wastewater at a decomposition rate above 0.

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Cardiovascular diseases are currently the leading cause of death globally and are projected to remain the leading cause in 2040, making heart rate an important physiological indicator that should be regularly monitored. Current heart rate monitoring techniques, including photoplethysmography and electrocardiography, are inconvenient for continuous biomonitoring in a wearable way. With a collection of compelling features, such as light weight and high sensitivity, triboelectric nanogenerators (TENGs) have become an emerging and cost-effective biotechnology for long-term and continuous heart rate monitoring in a wearable manner.

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MoonProt 3.0 (http://moonlightingproteins.org) is an updated open-access database storing expert-curated annotations for moonlighting proteins.

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