Publications by authors named "Sofia Collin"
Article Synopsis
- Cardiomyocytes in adult human hearts have a low regeneration rate of about 0.5% per year, raising questions about their role in heart failure recovery.
- Patients with advanced heart failure showed dramatically reduced cardiomyocyte renewal, with rates significantly lower than healthy individuals, while those with left ventricular assist devices (LVAD) experienced a notable increase in regeneration.
- These results suggest that the heart retains a potential for regeneration in disease states, which could be harnessed for future therapies.
Cardiomyocytes in the adult human heart show a regenerative capacity, with an annual renewal rate around 0.5%. Whether this regenerative capacity of human cardiomyocytes is employed in heart failure has been controversial.
View Article and Find Full Text PDFBackground: The present study aimed to assess whether the widespread concern of inferior cancer survival in adolescents and young adults (AYAs) compared with children and adults holds true in a Nordic setting with important differences in healthcare organisation compared with the United States (e.g. free access to healthcare) and the United Kingdom (e.
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