Publications by authors named "So Lim Shin"
Purpose: The aim of this study was to identify novel vaginal probiotics with the potential to prevent vulvovaginal candidiasis (VVC) and bacterial vaginosis (BV).
Materials And Methods: Eighteen strains of were isolated from healthy Korean women, and their antimicrobial effects against and were assessed. Three strains ( LM1203, LM1209, and LM1215) were selected for further investigation, focusing on their growth inhibition, biofilm regulation, and cellular mechanisms against these vaginal pathogens.
Background: Androgenetic alopecia (AGA) is a common and chronic problem characterized by hair follicle miniaturization.
Aims: In this study, heat-treated Limosilactobacillus fermentum LM1020 (HT-LM1020) was investigated in human follicle dermal papilla cell (HFDPC), scalp tissue, and clinical trials for patients with AGA.
Patients/methods: Cell proliferation and the expression of cyclins and cyclin-dependent kinases (CDKs) were measured in HFDPC.
Article Synopsis
- Probiotics like Lactobacillus gasseri LM1065 are live microorganisms that provide health benefits, and this particular strain was isolated from human breast milk and studied for its probiotic capabilities.
- The research involved genome mapping and assessing its resistance to gastric conditions, adherence to gut cells, and safety, showing it tolerated harsh stomach environments and displayed beneficial adherence properties.
- Additionally, the strain's cell-free supernatant (CFS) demonstrated antifungal effects against Candida albicans, highlighting its potential in preventing vaginal infections.
Purpose: Acne vulgaris is a common skin disease accompanied by chronic inflammation in the pilosebaceous follicles, resulting from excessive Cutibacterium acnes. This study aimed to investigate the inhibition of biofilm formation by C. acnes ATCC 6919 using heat-treated Pediococcus acidilactici LM1013 (HT-LM1013), previously isolated from the Korean traditional fermented alcoholic beverage-makgeolli, and its application as a leave-on-type product for patients with acne vulgaris.
View Article and Find Full Text PDFInvestigation of Immunostimulatory Effects of Heat-Treated LM1004 and Its Underlying Molecular Mechanism.
Food Sci Anim Resour
November 2022
Article Synopsis
- Postbiotics are inactivated probiotics that are more stable and beneficial for use in food and medicine compared to regular probiotics.
- The study focused on heat-treated LM1004 from kimchi, analyzing its fatty acid composition and immunostimulatory effects on macrophage cells, showing increased nitric oxide and cytokine production.
- Results indicate that HT-LM1004 activates specific signaling pathways (MAPK and NF-κB), enhancing immune responses, which could help in developing new food and pharmaceutical products.