Publications by authors named "Simone Willems"

Background: Endoscopic adrenalectomy by either transperitoneal laparoscopic (TLA) or posterior retroperitoneoscopic approach (PRA) is the preferred treatment for pheochromocytoma (PCC). PRA shows advantages in patient outcome, but blood pressure fluctuations may occur due to limited working space and increased CO-pressure. We investigated the impact of surgical technique on intraoperative hemodynamic instability in patients with PCC.

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Background: The use of low intra-abdominal pressure (<10 mmHg) reduces postoperative pain scores after laparoscopic surgery.

Objective: To investigate whether low-pressure pneumoperitoneum with deep neuromuscular blockade improves the quality of recovery after laparoscopic donor nephrectomy (LDN).

Design, Setting And Participants: In a single-center randomized controlled trial, 64 live kidney donors were randomly assigned to 6 or 12 mmHg insufflation pressure.

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Background: Since technique modifications of laparoscopic donor nephrectomy, e.g. retroperitoneoscopic donor nephrectomy or hand-assistance, have not shown significant benefit regarding safety or improvement of recovery, further research should focus on improving postoperative recovery.

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Background: Children with mitochondrial defects (MD) may have an increased risk for cardiorespiratory and neurological complications from anesthesia. The aim of this study was to determine the incidence of perioperative complications and adverse events in children with MD.

Methods: We performed a retrospective review of the anesthesia, surgical and medical records of 155 children up to 10 years who underwent a diagnostic surgical muscle biopsy for suspected mitochondrial and muscle disorders between 1999 and 2003.

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