Publications by authors named "Simone B Blaser"
Importance: There is clinical equipoise for COVID-19 convalescent plasma (CCP) use in patients hospitalized with COVID-19.
Objective: To determine the safety and efficacy of CCP compared with placebo in hospitalized patients with COVID-19 receiving noninvasive supplemental oxygen.
Design, Setting, And Participants: CONTAIN COVID-19, a randomized, double-blind, placebo-controlled trial of CCP in hospitalized adults with COVID-19, was conducted at 21 US hospitals from April 17, 2020, to March 15, 2021.
Article Synopsis
- The study explores an infant mouse model to understand the factors that influence the transmissibility of influenza A viruses, focusing on age, virus strain, and immune response.
- The research identifies that efficient virus shedding from the upper respiratory tract, young age of hosts, and close contact are crucial for transmission.
- The findings suggest that maternal immunity and the specific characteristics of the virus strain significantly impact transmission efficiency and susceptibility in the host.