Evaluation of changes in chemical composition and antioxidant activities from vine tea at different harvest times based on LC-MS, GC-MS, and data fusion algorithms.

This study systematically analyzed the chemical composition of vine tea using LC-MS and GC-MS to determine its optimal harvest time and key antioxidant compounds. By employing mass defect filtering (MDF) and a data fusion algorithm, the study examined compositional changes across different harvesting periods. The results identified 62 and 57 compounds through GC-MS and LC-MS, respectively.

A multi-level strategy based on comprehensive two-dimensional liquid chromatography-Q-Orbitrap-mass spectrometry combined with PLS regression model and RT-Ensemble Pred model to intelligently distinguish different geographical locations of Huanglian sample.

Huanglian (HL) is a member of the Ranunculaceae family, including Coptis chinensis Franch., Coptis deltoidea C. Y.

Emodin-8-O-β-D-glucopyranoside alleviates cholestasis by maintaining intestinal homeostasis and regulating lipids and bile acids metabolism in mice.

Cholestatic liver disease(CLD) is caused by impaired bile flow due to obstruction of the biliary tract, and long-term exposure to bile acids in the liver triggers inflammation, eventually leading to liver toxicity and liver fibrosis. Emodin-8-O-β-D-glucopyranoside(EG) is anthraquinone compound that is widely found in traditional Chinese medicine. It possessed antioxidative and anti-inflammatory activities.