Gentamicin Vestibulotoxicity: Further Insights From a Large Clinical Series.

Objective: To review insights gained from a 21-year experience with gentamicin-induced vestibulotoxicity including differences in vestibulotoxicity between single daily dosing (SDD) and multiple daily dosing (MDD) regimens.

Study Design: Retrospective case series.

Setting: Tertiary care center.

Transient Vertigo with Horizontal Nystagmus to Loud Noise and Pressure: Utricular Hydrops or Vestibular Atelectasis?

We present an unusual case of a patient with a positive Tullio phenomenon, brief Valsalva-induced transient horizontal nystagmus, reduced left caloric response, and bilateral vestibulo-ocular reflex loss. This study discusses the pathophysiology and differential diagnosis concerning the suspected pathology for the phenomenon of utricular hydrops or vestibular atelectasis and presents a literature review.

Vestibular Outcomes in Bilateral Posterior Semicircular Canal Occlusion for Refractory Benign Positional Vertigo.

Introduction: Bilateral posterior semicircular canal (PSCC) occlusion is a successful treatment of bilateral benign positional vertigo (BPV) refractory to particle repositioning manoeuvers. Little about the effects on the vestibular ocular reflex (VOR) postoperatively, which is the intent of this study.

Methods: All patients who underwent bilateral posterior canal occlusion for BPV at the University Health Network by the senior author (J.

Radiological features for the approach in trans-sphenoidal pituitary surgery.

Introduction: In order to perform trans-sphenoidal endoscopic pituitary surgery safely and efficiently it is important to identify anatomical and pituitary disease features on the pre-operative CT and MRI scans; thereby minimising the risk to surrounding structures and optimising outcomes. We aim to create a checklist to streamline pre-operative planning.

Methods: We retrospectively reviewed pre-operative CT and MRI scans of 100 adults undergoing trans-sphenoidal endoscopic pituitary surgery.

Inside implant criteria or not? - Detection of non-organic hearing loss during cochlear implant assessment.

Objectives: The diagnosis of non-organic hearing loss (NOHL) is a difficult but important issue during the assessment process for cochlear implantation (CI). We aim to identify the key factors in identifying patients with NOHL during CI assessment and present our local screening protocol for NOHL.

Methods: A retrospective review of patients referred to the Yorkshire Auditory Implant Service (YAIS) between 2003 and 2015 who were subsequently diagnosed with NOHL during the assessment.

Initial UK Experience With a Novel Magnetic Transcutaneous Bone Conduction Device.

Objective: To assess outcomes with a new transcutaneous bone conduction hearing aid.

Patients: Patients that underwent implantation with the transcutaneous bone conduction device between November 2013 and May 2014.

Intervention: Hearing rehabilitation using the BAHA Attract.

Bone-conduction hearing aids in an elderly population: complications and quality of life assessment.

To determine whether an elderly population with hearing impairment can be adequately rehabilitated with a bone-conduction hearing aid and whether the putative relationship between the elderly and an increased complication rate is justified. The study design was a retrospective case note review with a postal and telephone questionnaire, which was carried out in a tertiary centre. All patients aged 60 or over underwent implantation with a bone-conduction aid between 2009 and 2013 for conductive, SSD or mixed hearing loss.

Analysis of radiation-induced cell death in head and neck squamous cell carcinoma and rat liver maintained in microfluidic devices.

Objective: The aim of this study was to investigate how head and neck squamous cell carcinoma (HNSCC) tissue biopsies maintained in a pseudo in vivo environment within a bespoke microfluidic device respond to radiation treatment.

Study Design: Feasibility study.

Setting: Tertiary referral center.

Upper limb dysfunction following selective neck dissection: a retrospective questionnaire study.

Background: To determine total upper limb function following selective neck dissection over a mean follow-up of 1.6 years.

Methods: A retrospective questionnaire study in a tertiary head and neck surgical unit.