The Dynamic Field of Perioperative Treatment for Localized Muscle-Invasive Bladder Cancer: A Review of the Current Research Landscape.

: Muscle-invasive bladder cancer (MIBC) is associated with high recurrence and mortality rates. While cisplatin-based neoadjuvant chemotherapy followed by radical cystectomy remains the standard of care, many patients are ineligible for cisplatin. Recent advances in immunotherapy and biomarker research are reshaping perioperative strategies, aiming to personalize treatment and improve outcomes.

Impact of early surgical intervention on 1-year outcomes in patients hospitalized for macroscopic hematuria: a retrospective cohort study.

Purpose: To evaluate the impact of early surgical intervention on outcomes in patients admitted non-electively for macroscopic hematuria, a clinical scenario with limited prior research.

Methods: We conducted a single-center, retrospective observational study including 261 consecutive patients admitted non-electively with a primary diagnosis of macroscopic hematuria to the Urology Department at Hospital Universitario 12 de Octubre, Spain, between January 2016 and June 2021. Patients were stratified into three groups: no surgical intervention, surgical intervention within 5 days, and surgical intervention after 5 days.

Urine alkalinization for dissolution of uric acid stones and treatment of other urological diseases with a treatment combining potassium magnesium citrate and theobromine.

Background: Urine alkalinization can be used for the treatment of some urological diseases.

Methods: A series of cases showing the beneficial effects of urine alkalinization with potassium magnesium citrate, theobromine, zinc and vitamin A for the dissolution of uric acid stones and the treatment of other urological pathological conditions is presented.

Results: Alkalinization was effective in the dissolution of uric acid renal stones in various clinical conditions.

Assessing the influence of recurrent urinary tract infections on sexual function: a case-control study.

Background: Urinary tract infections (UTIs) significantly impact quality of life and can also lead to changes in sexual function.

Aim: This study aims to assess the symptoms associated with recurrent urinary tract infections (rUTIs) and their influence on both quality of life and sexual activity.

Methods: A case-control study was conducted, involving 383 patients with rUTIs and 161 healthy controls.

Extrauterine Retroperitoneal Leiomyomas: 3 Case Reports and Review of the Literature.

Leiomyomas are benign mesenchymal tumors which originate from smooth muscle cells. Extrauterine leiomyomas are rare and they may arise where smooth muscle cells are found. Their diagnosis is challenging due to their heterogeneous ways of presentation.

Ureteral Stenosis and Fistula after Kidney Transplantation.

Introduction: Ureteral complications after kidney transplantation are frequent and may have a negative impact on morbidity and graft function. Treatment modalities include conservative, endourological, and surgical techniques, with variable outcomes. The purpose of this study was to report the incidence, characteristics, treatment, and outcomes of ureteral complications at our center.