Publications by authors named "Shuto Fujita"
Background: The mechanisms by which neutrophils acquire pro-tumor properties remain poorly understood. In pancreatic cancer, cancer-associated fibroblasts (CAFs) may interact with neutrophils, directing them to promote tumor progression.
Methods: To validate the association between CAFs and neutrophils, the localization of neutrophils was examined in clinically resected pancreatic cancer specimens.
Background/aim: Diffuse-type gastric cancer (DGC) often forms peritoneal metastases, leading to poor prognosis. However, the underlying mechanism of DGC-mediated peritoneal metastasis is poorly understood. DGC is characterized by desmoplastic stroma, in which heterogeneous cancer-associated fibroblasts (CAFs), including myofibroblastic CAFs (myCAFs) and senescent CAFs (sCAFs), play a crucial role during tumor progression.
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- The splenic artery and vein are crucial for the blood flow of the remnant stomach after a distal gastrectomy (DG), influencing the surgical approach during procedures involving the stomach and pancreas.
- A 70-year-old man with early gastric cancer underwent simultaneous distal gastrectomy with Roux-en-Y reconstruction, distal pancreatectomy, and splenectomy, leading to the preservation of the remnant stomach's blood flow.
- Intraoperative indocyanine green (ICG) fluorescence was successfully used to evaluate blood flow, suggesting its effectiveness for similar future surgical contexts, though the patient experienced anastomosis edema post-surgery.
[A Case of Anaplastic Carcinoma Spindle Cell Type of the Pancreas].
Gan To Kagaku Ryoho
November 2017
Anaplastic carcinoma spindle cell type is an extremely rare disease and its prognosis is very poor. We herein report a case of anaplastic carcinoma spindle cell type of the pancreas. A 50-year-old man complaining of epigastralgia was found to have a pancreatic body-tail tumor by abdominal US and CT studies.
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